Browse the latest research summaries in the field of physiology for spinal cord injury patients and caregivers.
Showing 181-190 of 292 results
JOURNAL OF NEUROTRAUMA, 2019 • May 1, 2019
Herein, we describe the surgical and intraoperative electrophysiological approach used, followed by initial EES-enabled results observed in 2 human subjects with motor complete paralysis who were enro...
KEY FINDING: Positioning active electrodes at the rostral region of the array resulted in significantly higher EES-evoked motor response amplitudes in proximal leg muscles.
Respir Physiol Neurobiol, 2019 • March 1, 2019
This study examined the effects of cervical spinal cord contusion (C2SC) on NKCC1 and KCC2 expression in phrenic motor neurons of rats. The researchers found that 5 weeks post-C2SC, while individual e...
KEY FINDING: Membrane-bound NKCC1 expression was not significantly affected by C2SC, but the membrane/cytosolic ratio increased.
Journal of Musculoskeletal and Neuronal Interactions, 2019 • March 1, 2019
This study evaluated the applicability of current sarcopenia definitions in individuals with spinal cord injury (SCI). The study compared 31 men with complete SCI to 33 age-matched able-bodied men, as...
KEY FINDING: SCI subjects showed lower values in relative appendicular skeletal mass (RASM) and skeletal muscle index (SMI) compared to controls.
Neurology, 2019 • June 11, 2019
This study assessed the predictive value of midsagittal tissue bridges on MRI for sensorimotor recovery after cervical SCI. The width of dorsal tissue bridges correlated with sensory recovery and SEP ...
KEY FINDING: Greater width of dorsal midsagittal tissue bridges was associated with being sensory incomplete at 12 months, shorter SEP latencies, and greater SEP amplitudes.
PLoS ONE, 2019 • May 24, 2019
This study aimed to quantify urine production during electrical stimulation of the lower urinary tract using different stimulation frequencies in healthy volunteers. The study found that lower urinary...
KEY FINDING: Lower urinary tract electrical stimulation increased urine production per time compared to bladder diary baseline values.
Sensors, 2019 • July 27, 2019
This study characterizes traumatic spinal cord injury (TSCI) neurophysiologically using an intramuscular fine-wire electromyography (EMG) electrode pair. The results from the electrode pair data sugges...
KEY FINDING: The study found asymmetry in muscle activity between the left and right sides of the tail muscles before the injury, suggesting limb dominance.
Frontiers in Cellular Neuroscience, 2019 • August 9, 2019
The current study provides comprehensive investigation of the plasticity, integration, and neuromodulation of electrically evoked sensorimotor inputs in spinal motoneurons, and the resultant motor out...
KEY FINDING: EPSPs and coAPs of the S input exhibited progressive depression.
Clin Neurophysiol, 2012 • September 1, 2012
This study investigated the effect of limb segment load on soleus H-reflex amplitude and post activation depression in healthy individuals and one individual with chronic SCI. The results showed that ...
KEY FINDING: Limb segment load decreases post-activation depression of the soleus H-reflex in healthy adults.
Journal ofNeurology, Neurosurgery, and Psychiatry, 1990 • January 1, 1990
The electrical and contractile properties of motor units in hand muscles of quadriplegic subjects were studied before and after EMG biofeedback. The study found different classes of motor units, inclu...
KEY FINDING: Spontaneously active motor units and units that could only be slowly and weakly activated were observed, suggesting an overlap of surviving motor neurons.
Muscle Nerve, 2012 • November 1, 2012
This study investigated the effects of chronic paraplegia on skeletal muscle autophagy in rats. The researchers found that paraplegia led to an upregulation of autophagy markers in the soleus muscle. ...
KEY FINDING: SIRT1 protein expression was reduced by 37% in the paraplegia group compared to the control rats, indicating decreased SIRT1 signaling.