Browse the latest research summaries in the field of physiology for spinal cord injury patients and caregivers.
Showing 171-180 of 292 results
Top Spinal Cord Inj Rehabil, 2017 • January 1, 2017
Spinal cord injury can lead to alterations in cardiovascular autonomic function, resulting in low resting blood pressure, orthostatic hypotension, and autonomic dysreflexia. The mechanisms behind thes...
KEY FINDING: Individuals with SCI at or above the T6 neurologic level are at increased risk of AD during sexual stimulation. This risk increases with higher and more complete injuries.
J Physiol, 2018 • January 31, 2018
The study investigates the specific cervical spinal cells expressing A2A receptors responsible for phrenic motor facilitation (pMF). The researchers used siRNA injections to knock down A2A receptors i...
KEY FINDING: A2A receptors are highly expressed in motor neurons (including phrenic motor neurons) versus other cell types in the cervical spinal cord.
BioMed Research International, 2017 • December 27, 2017
This study investigated the pathological characteristics and stiffness of the gastrocnemius muscle (GM) in a rat model of spinal cord injury (SCI). The researchers used shear wave sonoelastography to ...
KEY FINDING: GM weights were decreased in the SCI model group compared to the control group, indicating muscle atrophy.
The Journal of Physiological Sciences, 2019 • March 29, 2018
The study examined the effects of isoflurane anesthesia on spinal cord neurovascular coupling in decerebrated rats during sciatic nerve stimulation. Results indicated that isoflurane did not significa...
KEY FINDING: Isoflurane anesthesia (1.2%) did not significantly alter LFP amplitude (p = 0.53) in the spinal cord of decerebrated rats.
The Journal of Physiology, 2018 • January 1, 2018
Spinal cord injury (SCI) in the cervical region increases the risk of obstructive sleep apnea (OSA). A study comparing individuals with and without SCI found impaired genioglossus (GG) muscle reflexes...
KEY FINDING: Individuals with SCI and OSA show impaired reflex activation of the genioglossus (GG) muscle, which helps keep the airway open.
Frontiers in Physiology, 2018 • May 18, 2018
This study investigated the acute cardiovascular effects of lumbosacral spinal cord epidural stimulation (scES) configured to facilitate motor activity in persons with SCI. The results showed that scE...
KEY FINDING: Spinal cord stimulation increased arterial blood pressure in individuals with SCI-induced cardiovascular deficits.
The Journal of Spinal Cord Medicine, 2019 • September 1, 2019
This study examined the impact of hybrid stimulation patterns, which combine paired-pulse doublets with constant-frequency background stimulation, on muscle torque in both paralyzed and non-paralyzed ...
KEY FINDING: Stimulation trains with doublets at both the start and middle yielded the most consistent enhancement of torque.
Spinal Cord Series and Cases, 2018 • June 19, 2018
The study examined the impact of self-guided training for the HandbikeBattle on fitness and body composition in individuals with spinal cord injury (SCI). It aimed to determine if training led to chan...
KEY FINDING: Training for the HandbikeBattle led to significant improvements in peak power output (POpeak).
BJU Int, 2019 • March 1, 2019
This study demonstrates that electrophysiological properties of the LUT are progressively impaired depending on SCI intensity and that intravesical P2X2/3R inhibition can attenuate electrical activity...
KEY FINDING: Severe SCI increased bladder contraction frequency and reduced bladder pressure amplitude and intraluminal-pressure high-frequency oscillations (IPHFO).
Arch Phys Med Rehabil, 2019 • June 1, 2019
This study investigated glucose metabolism differences among women with paraplegic and tetraplegic spinal cord injury (SCI) compared to able-bodied (AB) women, adjusting for body composition differenc...
KEY FINDING: Women with tetraplegia had higher glucose, insulin, and C-peptide concentrations at minute 120 during the oral glucose tolerance test (OGTT) compared to women with paraplegia and able-bodied women, even after adjusting for total body lean mass and percentage fat mass.