Browse the latest research summaries in the field of research methodology & design for spinal cord injury patients and caregivers.
Showing 531-540 of 607 results
BMJ Case Rep, 2013 • January 1, 2013
A 52-year-old man with cervical spondylosis sustained a hyperextension injury to the neck and subsequently developed central cord syndrome after 2 weeks. Owing to his spinal cord injury, an abdominal ...
KEY FINDING: Spinal cord injury can mask the typical signs and symptoms of an acute abdomen, making diagnosis challenging.
Clin Exp Immunol, 2021 • September 7, 2021
This review explores the proregenerative roles of Tregs in zebrafish and mammals, highlighting the FoxP3-dependent immunosuppressive function of Tregs in zebrafish as a useful model for future researc...
KEY FINDING: Zebrafish possess two FOXP3 orthologs, foxp3a and foxp3b, potentially serving a redundant role in Treg formation and activity.
Surgery, 2019 • February 1, 2019
This qualitative study explored how rehabilitation experiences influence patients' perceptions of function, identity, and coping in the context of tendon transfer surgery for tetraplegia. The study id...
KEY FINDING: Engagement in therapy was promoted by recognizing its necessity, achieving functional gains, and developing constructive patient-therapist relationships.
Scientific Reports, 2023 • September 26, 2023
This study investigates the feasibility of using ultrasound elastography (USE) to assess spinal cord injury (SCI) in a rabbit model in vivo. The researchers compared USE measurements with histological...
KEY FINDING: USE strain ratios were significantly higher in paralyzed rabbits compared to non-paralyzed rabbits, indicating differences in spinal cord mechanical properties.
Clin J Pain, 2018 • February 1, 2018
This study evaluated the effectiveness of the Vancouver Acute Neuropathic Pain Treatment Guideline (VANPTG) in assessing and diagnosing neuropathic pain (NP) in patients with traumatic spinal cord inj...
KEY FINDING: The incidence of NP was 56% in patients with traumatic SCI during acute hospital care.
Neural Regeneration Research, 2017 • May 1, 2017
This study introduces a novel method using low-energy two-photon nanosurgery to selectively disrupt individual dendrites, axons, and dendritic spines in the murine brain and spinal cord to accurately ...
KEY FINDING: Individual axons, dendrites, and dendritic spines in the brain and spinal cord were successfully ablated using low energy two-photon nanosurgery.
JOURNAL OF NEUROTRAUMA, 2014 • August 1, 2014
The MIASCI draft standard has been proposed to capture SCI experimental details, including the investigator, organism, behavior, surgery, perturbagens, histology, immunohistochemistry, imaging, biomat...
KEY FINDING: Transparent reporting standards for experiments using animal models of human SCI aim to reduce inherent bias and increase experimental value.
J Korean Med Sci, 2004 • January 1, 2004
This study developed a rat model of graded contusive spinal cord injury using a pneumatic impact device, demonstrating its reliability and reproducibility. The model allowed for controlled variation o...
KEY FINDING: Increasing impact velocity led to more severe functional impairments and greater damage to the spinal cord.
The Journal of Spinal Cord Medicine, 2018 • June 1, 2018
The editors of The Journal of Spinal Cord Medicine celebrate the journal's rising Impact Factor, reflecting its increasing influence in the field. This issue highlights the work of ASCIP members, ackn...
KEY FINDING: The Journal of Spinal Cord Medicine's Impact Factor increased significantly, indicating growing influence in the field.
Neural Regen Res, 2022 • June 1, 2022
This study aimed to identify key genes and pathways involved in axon regeneration after spinal cord injury (SCI) in zebrafish to provide new targets for mammalian SCI treatment. RNA sequencing data an...
KEY FINDING: Zebrafish spontaneously recovered 44% of their swimming ability within the subacute phase (2 weeks) after spinal cord injury.