Browse the latest research summaries in the field of research methodology & design for spinal cord injury patients and caregivers.
Showing 541-550 of 607 results
Spinal Cord Series and Cases, 2019 • June 1, 2019
This study describes methodological issues, experienced challenges related to data collection in North Macedonia and to discuss possible improvements of epidemiological data collection in future studi...
KEY FINDING: The study identified three major challenges with data collection in this setting: (1) research logistics and procedures, such as recruitment, infrastructure, and compensation, (2) ethical issues and the initial lack of mutual trust and understanding between researchers and participants, and (3) scientific quality and interpretation, including representativeness.
Frontiers in Endocrinology, 2020 • July 17, 2020
This review highlights the potential of zebrafish as a model for personalized regenerative medicine, particularly in the context of endocrine diseases. Zebrafish possess remarkable regenerative capabi...
KEY FINDING: Zebrafish possess regenerative capabilities in various organs, making them suitable for studying regenerative medicine approaches for endocrine disorders like diabetes mellitus.
Am J Case Rep, 2018 • November 19, 2018
This report is a single subject case study of a unique circumstance in which a patient was provided 2 treatment modalities in a manner creating a natural experimental design. Pain reduction was eviden...
KEY FINDING: Pain intensity decreased following SCS placement and CPRP.
Qual Life Res, 2018 • November 1, 2018
This study compares Ecological Momentary Assessment (EMA) and End-of-Day (EOD) diaries for measuring pain intensity and pain interference in individuals with spinal cord injury (SCI). The results indi...
KEY FINDING: Five days of EOD assessments are needed for excellent reliability in measuring pain intensity, while three days are sufficient for pain interference.
J Spinal Cord Med, 2008 • January 1, 2008
This review evaluated functional outcome measures for spinal cord injury (SCI) to determine their utility in clinical practice and research. The work group recommends that the latest version of the SC...
KEY FINDING: The Modified Barthel Index (MBI) has minimal evidence for validity and little clinical utility for use in the SCI population.
Spinal Cord Series and Cases, 2018 • June 4, 2018
The International Spinal Cord Injury (SCI) Lower Urinary Tract (LUT) Function Basic Data Set (version 2.0) was revised and reviewed to incorporate new knowledge and suggestions. Revisions include adop...
KEY FINDING: The revised data set adopts new terminology from the International Continence Society for adult neurogenic lower urinary tract dysfunction.
Not specified, 1998 • January 1, 1998
The study compares logistic regression, neural networks, and rough sets models in predicting ambulation at hospital discharge following spinal cord injury using the Spinal Cord Injury Model System dat...
KEY FINDING: All models performed well in predicting ambulation, with areas under the ROC curve in the 0.88-0.91 range.
Int J Qualitative Stud Health Well-being, 2011 • October 14, 2011
This qualitative interview study focuses on the personal experiences of partners to a spinal cord injured person. In the acute phase after the injury, partners also felt harmed, and support was needed...
KEY FINDING: In the acute phase after the injury, partners also felt harmed, and support was needed in relation to their own daily activities, eating, resting, and managing distress.
Journal of Pain Research, 2018 • May 17, 2018
This study introduces an ovine model of neuropathic pain that allows for the investigation of spinal cord stimulation (SCS) mechanisms through behavioral and electrophysiological measures. The model i...
KEY FINDING: Peroneal nerve constriction in sheep produces a reproducible large animal model of persistent neuropathic pain.
STAR Protocols, 2022 • March 18, 2022
Zebrafish regenerate their spinal cord after injury, both at larval and adult stages. Larval zebrafish have emerged as a powerful model system to study spinal cord injury and regeneration due to their h...
KEY FINDING: The protocol details two methods for spinal cord transection: incision and perforation lesion, both yielding comparable regeneration kinetics with reproducibility, high throughput, and low mortality.