Browse the latest research summaries in the field of aging for spinal cord injury patients and caregivers.
Showing 101-110 of 142 results
Can Fam Physician, 1994 • July 1, 1994
Elderly patients with spinal cord injuries can be rehabilitated successfully. Community home care resources are crucial for managing patients at home. Regular monitoring of skin integrity and for blad...
KEY FINDING: Elderly patients with spinal cord injuries can be rehabilitated successfully, even with flaccid paraplegia and lack of sensation.
International Journal of Clinical Pharmacy, 2021 • October 9, 2020
The study investigated the potential of montelukast, a leukotriene receptor antagonist, to alleviate age-related neurological decline using Norwegian registry data. The results suggested that previous...
KEY FINDING: Previous use of montelukast correlated with improved scores on cognitive or neurological functioning.
Molecules, 2021 • April 1, 2021
The study investigated the roles of GAL2-R and GAL3-R in learning, memory, and anxiety in young and aging mice. Knockout mice lacking either receptor were subjected to behavioral tests and analyses of...
KEY FINDING: Loss of GAL3-R, but not GAL2-R, slowed learning and induced anxiety in older (12–14-month-old) mice.
Oxidative Medicine and Cellular Longevity, 2022 • March 16, 2022
This study investigates the role of GIT1 in regulating axon growth within the inflammatory environment following spinal cord injury (SCI). The research found that GIT1 promotes axon growth by phosphor...
KEY FINDING: GIT1 knockout mouse neurons exhibited restricted axon growth in an inflammatory environment, highlighting GIT1's role in promoting growth under such conditions.
European Journal of Trauma and Emergency Surgery, 2022 • May 21, 2022
This retrospective cohort study aimed to differentiate geriatric odontoid fractures into stable (SFs) and unstable fractures (UFs) based on angulation and displacement, correlating this classification...
KEY FINDING: The classification into SFs and UFs was significant for its angulation (P = 0.0006) and displacement (P < 0.0001).
Front. Cell. Neurosci., 2023 • July 28, 2023
This study investigates the age-related changes in cortical immature neurons (cINs) within the piriform cortex of mice, focusing on their numbers, morphology, and marker expression from postnatal stag...
KEY FINDING: The study found a significant decrease in the number of cINs in the piriform cortex as mice aged, particularly between 1 and 12-15 months.
Aging Cell, 2023 • August 7, 2023
This study investigates the maturation of dormant neuronal precursors in the adult and aged brain using transgenic mice. The research questions whether the aging process affects the awakening and matu...
KEY FINDING: Dormant precursors can awaken and mature into adult-matured neurons (AM) even at old age, indicating that protracted immaturity does not prevent late awakening.
Frontiers in Endocrinology, 2023 • November 8, 2023
This study employed Mendelian randomization to investigate the causal relationship between sarcopenic obesity (SO) factors and benign prostatic hyperplasia (BPH), focusing on basal metabolic rate (BMR...
KEY FINDING: An increase in BMR is associated with an elevated risk of developing BPH.
Nature Communications, 2015 • October 27, 2015
The present work demonstrates that the anti-asthmatic drug and leukotriene receptor antagonist montelukast restores learning and memory function in old rats. Montelukast treatment reduced age-associat...
KEY FINDING: Montelukast treatment significantly improved task learning in old rats to a level comparable to young ones.
J. Clin. Med., 2024 • March 8, 2024
This meta-analysis provides the summary estimates for perioperative and postoperative functional outcome and safety of endoscopic treatment options for BPO in patients ≥75 years of age. Of particular ...
KEY FINDING: All surgical techniques significantly improve the postoperative quality of life of patients in this age group compared to their preoperative quality of life.