Browse the latest research summaries in the field of cardiovascular science for spinal cord injury patients and caregivers.
Showing 191-200 of 309 results
AGING, 2021 • May 17, 2021
This study identified nine prognostic immune genes in extranodal diffuse large B-cell lymphoma (EN DLBCL) and established a multivariate predictive model based on these genes, demonstrating that patie...
KEY FINDING: Nine prognostic immune genes were identified in EN DLBCL, including IFNA21, KIR2DL1, MUCL1, SFTPA2, MX1, USP18, CCL1, IGLV1-36, and GLP1R.
npj Regenerative Medicine, 2021 • July 2, 2021
This study demonstrates that adult X. tropicalis can regenerate heart tissue after ventricular apex resection, primarily through cardiomyocyte proliferation. RNA-seq analysis identified Fosl1 as a key...
KEY FINDING: Cardiomyocyte proliferation greatly contributes to heart regeneration in adult X. tropicalis upon apex resection.
Cell Death and Disease, 2021 • September 3, 2021
This study profiles transcriptomes and proteomes in a mouse model of AMI, revealing early immune system activation and pyroptosis. VX-765, a pyroptosis inhibitor, reduced infarct size and improved hea...
KEY FINDING: Immune system activation and subsequent pyroptosis occur in the early stages (6-24 hours) of AMI in a mouse model.
Cells, 2021 • November 26, 2021
This study introduces a scalable workflow for purifying immunomodulatory AML-EVs and compares their phenotype and function to parental AML cells and secreted soluble factors. AML-EVs were enriched usi...
KEY FINDING: AML-EVs showed a significant dose-dependent inhibition of T cell proliferation, unlike AML cells or their soluble factors.
Cell Reports Medicine, 2025 • March 18, 2025
The study develops injectable GelMA hydrogels with controlled mechanical properties containing targeting miR-222-engineered extracellular vesicles (TeEVs). These injectable patches facilitate the prec...
KEY FINDING: Targeting miR-222-engineered EVs are incorporated in mechanical GEL hydrogels
CELL CYCLE, 2016 • March 3, 2016
This study investigates the potential of hair follicle-associated pluripotent (HAP) stem cells to differentiate into cardiac muscle cells and form beating heart-muscle tissue sheets in vitro. The find...
KEY FINDING: Isoproterenol significantly enhances the differentiation of HAP stem cells into cardiac muscle cells in vitro compared to non-supplemented conditions.
Neural Regeneration Research, 2017 • July 1, 2017
This study investigated the protective effects of aldehyde dehydrogenase 2 (ALDH2) against spinal cord ischemia/reperfusion injury (SCII) in rats. The researchers found that alcohol administration, wh...
KEY FINDING: Rats treated with alcohol after SCII induction displayed improved neurological function, as evidenced by higher Basso, Beattie, and Bresnahan (BBB) scores.
Scientific Reports, 2020 • May 6, 2020
This study investigates the role of miRNAs in lipedema by comparing the extracellular miRNA profiles of SVF cells from healthy individuals and lipedema patients. The results showed that sEV-contained ...
KEY FINDING: sEVs showed no significant difference in size or concentration between healthy and lipedema patients.
PLOS ONE, 2020 • August 11, 2020
This study investigated the efficacy of nonviral retrograde gene transfer of human hepatocyte growth factor (HGF) in improving ischemic neuropathy using a rat model of ischemic-reperfusion nerve injur...
KEY FINDING: HGF gene transfer significantly improved mechanical allodynia and thermal hyperalgesia in rats with ischemic-reperfusion nerve injury (IRI).
Journal of Molecular Neuroscience, 2021 • September 8, 2020
This study investigates the effect of microtubule stabilization on microcirculation reconstruction after spinal cord injury (SCI). The results showed that microtubule stabilization promotes angiogenes...
KEY FINDING: Microtubule stabilization promotes microcirculation reconstruction after SCI by increasing the number of microvessels, pericytes, and perfused microvessels.