Browse the latest research summaries in the field of cardiovascular science for spinal cord injury patients and caregivers.
Showing 281-290 of 309 results
Respir Physiol Neurobiol, 2019 • July 1, 2019
This review discusses how local circulatory control and oxygen delivery in the spinal cord regulate different pathways to phrenic motor plasticity. Acute intermittent hypoxia (AIH) elicits distinct me...
KEY FINDING: Moderate AIH induces serotonin-dependent pLTF, which is independent of tissue hypoxia and relies on carotid body chemoreceptor activation.
The Journal of Spinal Cord Medicine, 2017 • September 1, 2017
This retrospective study analyzed serum lipid profiles in 269 SCI patients, correlating them with disease duration, lesion level/grade, and ambulation status to assess dyslipidemia risk factors. The s...
KEY FINDING: Total cholesterol, LDL cholesterol, and triglycerides were higher than normal in 21.2%, 24.4%, and 31% of the patients, respectively.
The Journal of Spinal Cord Medicine, 2018 • July 1, 2018
This review describes the current state of cIMT acquisition and analysis quality in individuals with SCI. The primary finding of this review is that the current literature reporting cIMT values among ...
KEY FINDING: The study found that the overall reporting of quality methodology for cIMT in SCI literature was poor.
Leukemia, 2016 • January 29, 2016
This study by the European Research Initiative on CLL (ERIC) identified and validated a flow-cytometric approach to reliably quantitate CLL cells to the level of 0.0010% (10 −5). A parallel analysis o...
KEY FINDING: A six-marker flow cytometry panel (CD19, CD20, CD5, CD43, CD79b, and CD81) was identified as reliable and convenient for identifying typical CLL cells.
Eur Spine J, 2009 • March 28, 2009
This case report describes a 47-year-old male who suffered a traumatic C7–D1 dislocation and experienced severe bradycardia with multiple episodes of cardiac arrest for two months post-injury. Despite...
KEY FINDING: A patient with a cervico-dorsal (C7-D1) spinal injury experienced persistent and recurrent cardiac arrests that did not resolve within the expected 4-6 weeks.
Neurospine, 2022 • December 1, 2022
Traumatic spinal cord injury (SCI) disrupts the spinal cord vasculature resulting in ischemia, amplification of the secondary injury cascade and exacerbation of neural tissue loss. Restoring functiona...
KEY FINDING: Five main therapeutic approaches to diminish hypoxia-ischemia and promote vascular repair were identified as (1) the application of angiogenic factors, (2) genetic engineering, (3) physical stimulation, (4) cell transplantation, and (5) biomaterials carrying various factor delivery.
Top Spinal Cord Inj Rehabil, 2017 • July 1, 2017
The inflammatory response plays a significant role in both the acute and chronic phases of SCI as an interrelated, multifactorial process that adversely impacts health and quality of life after injury...
KEY FINDING: Chronic inflammation worsens secondary medical complications and amplifies the risk for cardiometabolic disorders after injury, directly impacting both the quality of life and mortality risk after SCI.
JOURNAL OF NEUROTRAUMA, 2009 • July 1, 2009
The study aimed to determine if initiating swim training acutely after spinal cord injury (SCI) is more beneficial than initiating it after 2 weeks. Rats with moderate to severe thoracic contusion SCI...
KEY FINDING: Acute swim training (initiated 3 days post-SCI) is less effective than training initiated at 2 weeks post-injury in improving swimming ability.
American Journal of Pathology, 2019 • July 1, 2019
This review discusses the role of pericytes in spinal cord injury, focusing on their involvement in scar formation and potential as therapeutic targets. A specific subset of pericytes (Glast+) contrib...
KEY FINDING: A subset of pericytes (Glast+) contributes significantly to fibrotic scar formation after spinal cord injury in mice.
The Journal of Spinal Cord Medicine, 2017 • January 1, 2017
The study aimed to determine the inter-day reliability of blood pressure (brachial and finger) and cerebral blood flow velocity (CBFv) assessments in individuals with spinal cord injury (SCI) and able...
KEY FINDING: Brachial blood pressure assessment showed fair to substantial inter-day reliability.