Browse the latest research summaries in the field of critical care for spinal cord injury patients and caregivers.
Showing 1-10 of 44 results
J. Clin. Med., 2023 • March 20, 2023
This study aimed to develop a risk score for predicting delirium in elderly patients with cervical spinal cord injury (SCI) and/or cervical fracture, using data from a retrospective cohort study of 15...
KEY FINDING: The study identified six key factors that contribute to the risk of delirium: old age (≥80 years), hypoalbuminemia, cervical fracture, major organ injury, dependence on pre-injury mobility, and comorbid diabetes.
BMJ Open, 2023 • January 1, 2023
This study is a single-center randomized controlled trial designed to assess the efficacy of mechanical insufflation-exsufflation (MI-E) in reducing the duration of mechanical ventilation for neurolog...
KEY FINDING: The primary endpoint of this trial is the duration of mechanical ventilation from randomisation until successful weaning.
Journal of Neurotrauma, 2023 • December 1, 2023
This study evaluated the effects of neurogenic, inflammatory, and infective fevers on acutely injured human spinal cords, using data from 86 patients with severe traumatic spinal cord injuries. The fi...
KEY FINDING: High fever occurred in 76.7% of patients with acute, severe traumatic spinal cord injuries.
Molecular Medicine, 2024 • November 7, 2024
This study investigates the causal relationship between mitochondrial abnormalities and chronic post-sepsis muscle weakness, exploring potential therapeutic targets. The findings demonstrate that post...
KEY FINDING: Post-sepsis skeletal muscle weakness develops progressively after the resolution of acute sepsis and is linked to mitochondrial abnormalities.
JOURNAL OF REHABILITATION MEDICINE, 2025 • January 3, 2025
This case report describes a young woman who developed severe bilateral heterotopic ossification (HO) on the anteromedial sides of her knees after an intensive care unit (ICU) stay following complicat...
KEY FINDING: Early surgical resection of heterotopic ossification (HO) in the knee, performed just 4 months after symptom onset, resulted in a good clinical and functional outcome for a young woman.
Critical Care, 2025 • January 22, 2025
As part of the PROMPT-SCI trial, 45 adult patients were recruited from a single Level-1 trauma center in Montreal, Canada, between April 2021 and August 2023. The intervention consisted of daily 30-mi...
KEY FINDING: This study supports the safety and feasibility of passive in-bed leg cycling in ICU patients with severe TSCI.
The Journal of Spinal Cord Medicine, 2021 • January 1, 2021
This study investigated the association between high tidal volume ventilation (HVtV) and ventilator-associated pneumonia (VAP) in patients with acute cervical spinal cord injury (SCI). The study found...
KEY FINDING: HVtV was associated with a 1.96 relative risk of VAP development (95% credible interval 1.55–2.17) on Bayesian analysis.
The Journal of Spinal Cord Medicine, 2022 • July 1, 2022
This scoping review synthesized existing literature on decannulation in SCI patients, identifying 26 eligible publications primarily from physical medicine, neurology, and pulmonary/critical care fiel...
KEY FINDING: Interdisciplinary tracheostomy teams (ITT) improve communication and operational processes, enhancing decannulation outcomes.
Global Spine Journal, 2022 • July 1, 2022
This retrospective study analyzed the outcomes of cervical SCI patients admitted to the ICU of a trauma center in Nepal between May 2017 and August 2018. The study found that fall injuries were the mo...
KEY FINDING: Fall injuries were the most common cause of cervical SCI, accounting for 83.3% of cases.
Ann. Intensive Care, 2021 • October 12, 2021
This systematic review and meta-analysis examined weaning outcomes in mechanically ventilated patients with SCI, finding that approximately 63% of patients in the ICU could be weaned from the ventilat...
KEY FINDING: In ICU, the mean duration of mechanical ventilation was 27 days, with a weaning success rate of 63% and a mortality rate of 8%.