Browse the latest research summaries in the field of critical care for spinal cord injury patients and caregivers.
Showing 31-40 of 44 results
Intensive Care Med, 2020 • January 21, 2020
This study established three distinct treatment protocols, each with three tiers whereby higher tiers involve therapies with higher risk. One protocol addresses the management of ICP elevation when br...
KEY FINDING: Established three distinct treatment protocols for managing sTBI patients with combined ICP and brain oxygen monitoring: one for ICP elevation with normal brain oxygenation, one for brain hypoxia with normal ICP, and one for both conditions present.
Crit Care Med, 2020 • June 1, 2020
This study identified the major causes of morbidity and mortality in critically ill children using detailed assessments of individual patients. Low cardiac output and cardiac arrest, inflammation-rela...
KEY FINDING: The most common problems were related to poor delivery of essential substances like oxygen to the body, inflammation, and direct injury to tissues, especially the brain.
Acute and Critical Care, 2025 • February 1, 2025
This paper presents two case reports detailing the successful use of droxidopa to manage hypotension in acute spinal cord injury (SCI) patients who could not tolerate midodrine due to reflex bradycard...
KEY FINDING: Droxidopa was successfully used to manage hypotension in two patients with acute SCI who experienced bradycardia with midodrine.
Hospital Pharmacy, 2024 • January 1, 2024
This retrospective study evaluated the efficacy and safety of enteral midodrine in facilitating the weaning of IV vasopressors in acute traumatic spinal cord injury patients. The study found that mido...
KEY FINDING: 79.2% of patients successfully weaned off IV vasopressors after the addition of midodrine.
Korean J Neurotrauma, 2024 • December 26, 2024
Acute SCI requires a multidisciplinary approach for optimal management, focusing on both primary and secondary injury processes. Surgical decompression within 24 hours and early neurointensive care ar...
KEY FINDING: Early decompressive surgery within 24 hours post-injury is widely supported for patients with spinal instability or cord compression, enhancing motor recovery, especially in incomplete SCI.
Trauma Surg Acute Care Open, 2025 • January 1, 2025
This retrospective study evaluated the association between prophylactic iNPPV and the incidence of pneumonia in patients with acute CSCIs. The study included 94 patients diagnosed with CSCIs with ASIA...
KEY FINDING: Prophylactic iNPPV was associated with a lower incidence of pneumonia compared to usual care in patients with acute CSCIs.
Curr Opin Crit Care, 2025 • April 1, 2025
The timing of spinal decompression and hemodynamic management may impact neurological function, however, because of the deficiencies of current studies, individualized, patient-tailored decision-makin...
KEY FINDING: Early decompression (within 24 hours) may improve neurological outcomes, but the evidence is not definitive and may be influenced by study methodology and patient heterogeneity.
World Journal of Gastroenterology, 2025 • February 28, 2025
Neurosurgical patients face a high risk of stress ulcers and gastrointestinal bleeding due to factors like brain injury, spinal cord injury, and increased intracranial pressure. The review discusses b...
KEY FINDING: Stress ulcers are a significant risk for neurosurgical patients, particularly those with severe brain injuries and elevated intracranial pressure.
The Journal of Spinal Cord Medicine, 2017 • March 1, 2017
This study examines the use of extracorporeal lung support (ECMO and iLA) in patients with spinal cord injury (SCI) and post-traumatic lung failure. The results suggest that ECMO is a feasible and pot...
KEY FINDING: All 5 ECMO-supported patients were successfully weaned, and one of the two iLA-treated patients was weaned from the device.
Journal of Neuroinflammation, 2016 • September 28, 2016
Post-SCI multiple organ dysfunction is influenced by multifactorial mechanisms, and the extent to which systemic inflammation and immune depression contribute to SCI-associated complications is still ...
KEY FINDING: SCI triggers systemic inflammatory responses, marked by increased immune cells and pro-inflammatory mediators, leading to inflammation in secondary organs.