Browse the latest research summaries in the field of critical care for spinal cord injury patients and caregivers.
Showing 21-30 of 44 results
Handb Clin Neurol, 2015 • January 1, 2015
Autonomic dysfunction can occur after traumatic brain injury due to damage to the central autonomic network (CAN), affecting the balance of excitatory and inhibitory inputs to ANS effector organs. Isc...
KEY FINDING: Ischemic strokes, especially insular strokes, may cause cardiac autonomic dysregulation, potentially leading to subendocardial hemorrhages and myocardial infarction.
Spinal Cord Series and Cases, 2016 • July 14, 2016
This case report describes a unique instance of critical illness myopathy (CIM) in a 23-year-old male who sustained a cervical spine injury and was admitted to the ICU. The patient developed significa...
KEY FINDING: A 23-year-old male with a cervical spine injury developed critical illness myopathy (CIM) while in the ICU, a previously unreported occurrence.
Cochrane Database of Systematic Reviews, 2017 • January 3, 2019
We screened 2686 citations and included two trials enrolling 95 participants and one cohort study enrolling 17 participants. One trial reported a statistically significant reduction in mechanical vent...
KEY FINDING: One trial of 75 participants reported that extubation success (defined as no need for reintubation within 48 hours) was higher in the mechanical insufflation-exsufflation (MI-E) group (82.9% versus 52.5%, P < 0.05)
Spinal Cord, 2017 • June 1, 2017
This retrospective study analyzed data from 36 patients with cervical spinal cord injuries (C1-C5) to assess the impact of theophylline treatment on ventilator weaning success, using a non-linear, cat...
KEY FINDING: Ninety-two percent of patients achieved 16 hours ventilator-free breathing (VFB), and 83% achieved 24 hours VFB.
J Spinal Cord Med, 2006 • January 1, 2006
This case report describes a 33-year-old man with refractory spasticity who experienced acute intrathecal baclofen (ITB) toxicity leading to deep coma within minutes of drug administration. The patien...
KEY FINDING: The patient developed respiratory difficulty, a generalized seizure, and coma minutes after ITB administration.
J Spinal Cord Med, 2008 • January 1, 2008
This study aimed to identify the best predictors of ventilator weaning success in patients with high cervical spinal cord injuries. The study retrospectively reviewed data from 26 ventilator-dependent...
KEY FINDING: Failure to wean off the ventilator completely was predicted by absence of motor unit recruitment of one hemidiaphragm or at least moderate decreased recruitment with needle electromyography (EMG) in both hemidiaphragms.
The Journal of Spinal Cord Medicine, 2011 • January 1, 2011
This study assessed the effect of timing and technique of tracheostomy on morbidity, mortality, and resource utilization in patients with acute traumatic spinal cord injuries (SCIs) undergoing mechani...
KEY FINDING: Early tracheostomy (<7 days after intubation) was associated with shorter duration of mechanical ventilation and ICU stay compared to late tracheostomy (≥7 days).
Cureus, 2018 • September 27, 2018
This case report presents the first documented instance of using REBOA in a trauma patient suffering from neurogenic shock. The utilization of REBOA as an adjunct to standard resuscitation methods hel...
KEY FINDING: REBOA was successfully used as an adjunct to manage neurogenic shock in a trauma patient, maintaining cardiac and cerebral perfusion.
Spinal Cord Series and Cases, 2019 • March 11, 2019
This study investigated the clinical care of respiratory dysfunction, oropharyngeal dysphagia and nutrition in CSCI patients within specialized and non-specialized units across the UK. The survey resu...
KEY FINDING: Non-specialized units showed variations in respiratory management, including limited use of vital capacity measures and graduated weaning programs.
Intensive Care Medicine Experimental, 2024 • January 10, 2024
This review summarizes translational research using zebrafish to study sepsis, organ failure, and trauma, highlighting technologies applicable in this model organism. Zebrafish models allow visualizat...
KEY FINDING: LPS-induced zebrafish endotoxemia results in extravascular migration of neutrophils and macrophages and changes in the expression of tight junction proteins.