Browse the latest research summaries in the field of dentistry for spinal cord injury patients and caregivers.
Showing 1-5 of 5 results
Stem Cells International, 2019 • September 15, 2019
This article reviewed roles of DFCs in tooth development, their properties, and clinical application potentials, thus providing a novel guidance for tissue engineering. The establishment of tooth root...
KEY FINDING: DFCs robustly expressed parathyroid hormone-related peptide (PTHrP) during tooth root formation and after tooth eruption, and PTHrP+ DFCs differentiated into PDLCs, alveolar cryptal bone osteoblasts, and cementoblasts in acellular cementum
The Journal of Neuroscience, 1984 • September 1, 1984
This study investigates the trans-synaptic effects of peripheral nerve injury on second-order neurons in the medullary dorsal horn following tooth pulp extirpation in cats. The study demonstrates that...
KEY FINDING: Peripheral nerve injury leads to cavity formation within the dendrites of second-order neurons in laminae I and II of the medullary dorsal horn.
International Journal of Nanomedicine, 2025 • March 8, 2025
The study successfully constructed a hydrogel-loaded lyophilized hucMSCs-exo drug delivery system, which is called exo@H, and demonstrated its effectiveness in treating periodontitis in mice. Exo@H pr...
KEY FINDING: Lyophilized hucMSCs-exo promoted the proliferation and osteogenic differentiation of MC3T3-E1 cells, and showed more significant abilities in combination with hydrogel.
Journal of Oral Biology and Craniofacial Research, 2017 • February 4, 2017
Stem cells possess self-renewal and differentiation capabilities, holding potential for treating various conditions, including tooth loss. Dental stem cells, easily accessible, offer promise in treati...
KEY FINDING: Dental stem cells are found in primary and permanent teeth, including wisdom teeth, making them a readily available resource.
Frontiers in Pharmacology, 2021 • July 20, 2021
bFGF is involved in all stages of pulp repair/regeneration and uses different intracellular signaling pathways to control specific biological processes, which may be determined by cell origins and trea...
KEY FINDING: bFGF acts through binding to tyrosine kinase FGF receptors on the cell membrane, triggering intracellular signaling pathways that initiate cell migration, proliferation, and differentiation.