Browse the latest research summaries in the field of endocrinology for spinal cord injury patients and caregivers.
Showing 101-110 of 211 results
Spinal Cord Series and Cases, 2016 • April 7, 2016
This retrospective case series evaluated the effectiveness of high-amplitude penile vibratory stimulation (PVS) for sperm retrieval in anejaculatory Asian men with spinal cord injury (SCI). The study ...
KEY FINDING: The overall ejaculatory success rate using high amplitude PVS was 46.15%.
J Neurotrauma, 2017 • November 1, 2017
This study aimed to determine if testosterone (TE) prevents bone deficits post-spinal cord injury (SCI) and if finasteride (FIN) is required for TE-induced skeletal preservation. The study found that ...
KEY FINDING: TE+FIN prevented the chronic cancellous bone deficits and LABC muscle loss in SCI animals without inducing prostate enlargement.
BMJ Open, 2017 • July 4, 2017
This study investigates the effects of evoked resistance training (RT) combined with testosterone replacement therapy (TRT) on body composition and metabolic profiles in men with chronic, motor comple...
KEY FINDING: The trial will investigate the use of surface neuromuscular electrical stimulation-induced resistance training (NMES-RT) to restore muscle size after spinal cord injury (SCI).
The Journal of Spinal Cord Medicine, 2017 • March 1, 2017
A recent study showed weight loss in SCI patients, but the author argues that BMI alone is insufficient to assess health in this population due to changes in body composition. Body composition, partic...
KEY FINDING: Persons categorized as overweight or obese at baseline experienced overall weight loss over 1 year, while those initially characterized as underweight or of normal weight appeared to gain weight.
J. Biol. Chem., 2017 • May 2, 2017
This study investigates how muscle-released products interact with bone cells to influence their function, focusing on myostatin's role in muscle-bone interaction. Myostatin directly targets osteocyte...
KEY FINDING: Myostatin increases the expression of SOST, DKK1, and RANKL in osteocytes, which are important regulators in bone remodeling.
J Spinal Cord Med, 2007 • January 1, 2007
This study confirms and extends prior work that reported a reduction in stimulated GH release in persons with SCI, which was related to baseline values. The study found that twins with SCI have marked...
KEY FINDING: Twins with SCI had a significantly lower body mass index (BMI) than non-SCI twins.
J Spinal Cord Med, 2009 • August 1, 2009
This systematic review examined the effect of exercise on carbohydrate and lipid metabolism disorders in adults with chronic SCI. Twenty-two studies were included, but the evidence was deemed insuffic...
KEY FINDING: Evidence is insufficient to determine whether exercise improves carbohydrate and lipid metabolism disorders among adults with SCI.
J Spinal Cord Med, 2010 • February 1, 2010
This case report describes the successful use of intravenous conivaptan to treat symptomatic hyponatremia in a 57-year-old man with tetraplegia undergoing neurologic rehabilitation. The patient's hypo...
KEY FINDING: Intravenous conivaptan was effective in inducing and maintaining normal sodium levels (eunatremia) in a patient with protracted hyponatremia resistant to standard therapies.
The Journal of Spinal Cord Medicine, 2011 • January 1, 2011
This retrospective chart review aimed to define the temporal course of weight gain in persons with new SCI and identify predictors of weight gain. The study found a significant increase in BMI after n...
KEY FINDING: Mean BMI increased significantly after SCI, with the greatest increase occurring during the first year post-injury.
The Journal of Spinal Cord Medicine, 2018 • January 1, 2018
This mini-review presents evidence for TRT as a potential strategy to aid in the management of body composition changes and to improve metabolism in persons with SCI. In the absence of adequate studie...
KEY FINDING: Transdermal TRT can increase LBM and reduce FM over 3–36 months, relative to placebo, in hypogonadal elderly men and to a lesser extent in men with SCI.