Browse the latest research summaries in the field of endocrinology for spinal cord injury patients and caregivers.
Showing 111-120 of 211 results
The Journal of Spinal Cord Medicine, 2018 • July 1, 2018
This study aimed to determine the effects of dietary vitamin D intake on insulin sensitivity (Si), glucose effectiveness (Sg), and lipid profile in individuals with spinal cord injury (SCI). The key f...
KEY FINDING: Individuals with higher vitamin D intake had significantly lower total cholesterol levels compared to those with lower intake (P = 0.035).
The Journal of Spinal Cord Medicine, 2017 • September 1, 2017
This systematic review aimed to identify and compare the effectiveness of various interventions for managing obesity in individuals with chronic SCI. The review found that bariatric surgery produced t...
KEY FINDING: Bariatric surgery resulted in the greatest and most sustained weight loss and BMI correction in individuals with chronic SCI.
Physiol Rep, 2017 • September 1, 2017
This study demonstrates that severe immobilization following SCI leads to significant bone loss and reduced bone turnover in mice. Daily administration of PTH protects against SCI-induced bone loss by...
KEY FINDING: SCI-vehicle animals exhibited a marked decrease in proximal tibial fractional trabecular bone volume and trabecular thickness compared to the control sham-vehicle group.
The Journal of Spinal Cord Medicine, 2019 • January 1, 2019
This study investigated the prevalence of metabolic syndrome in veterans with spinal cord injury (SCI) using modified International Diabetes Federation (IDF) criteria. The results indicated a high pre...
KEY FINDING: Over 57% of the veterans assessed were determined to have metabolic syndrome by modified IDF criteria, including 76.7% with BMI ≥22 kg/m2.
Physiol Rep, 2018 • January 1, 2018
This study elucidates the mechanisms by which nandrolone stimulates the differentiation of myogenic lineage cells, focusing on the roles of MyoD and Numb. The research demonstrates that androgens stim...
KEY FINDING: Nandrolone increases both MyoD mRNA and protein expression in C2C12 myoblasts, indicating an upregulation of MyoD production.
Spinal Cord, 2018 • September 1, 2018
The study demonstrated that adiponectin is closely related to body composition and metabolic profile in persons with SCI The links between adiponectin levels and the size of paralyzed muscle suggest p...
KEY FINDING: Adiponectin was negatively related to both total and regional fat mass and positively related to lean mass and muscle mass.
Physiol Rep, 2018 • September 1, 2018
This study investigates the effects of myostatin on insulin action and glucose uptake in C2C12 muscle cells. Myostatin, known for its role in inhibiting muscle growth, is shown to impair insulin-stimu...
KEY FINDING: Myostatin significantly reduced basal and insulin-induced IRS-1 tyrosine phosphorylation, expression and activation of PI3K, associated with diminished AKT phosphorylation and elevated GSK3b phosphorylation.
Arch Phys Med Rehabil, 2019 • June 1, 2019
This study investigated glucose metabolism differences among women with paraplegic and tetraplegic spinal cord injury (SCI) compared to able-bodied (AB) women, adjusting for body composition differenc...
KEY FINDING: Women with tetraplegia had higher glucose, insulin, and C-peptide concentrations at minute 120 during the oral glucose tolerance test (OGTT) compared to women with paraplegia and able-bodied women, even after adjusting for total body lean mass and percentage fat mass.
Spinal Cord, 2019 • March 1, 2019
The findings demonstrated that multiple indicators of cardiometabolic health and body composition variables are associated with serum T levels in men with motor complete SCI. The low range serum T gro...
KEY FINDING: Low range serum T group had greater total (9.6%, P= 0.04) percentage fat mass and visceral adipose tissue (VAT) area (72%, P= 0.01) compared to normal range serum T group.
Journal of Clinical Medicine, 2019 • January 23, 2019
This study investigated the effects of environmental lighting conditions on neural repair following experimental spinal cord injury (SCI) in rats, focusing on the role of endogenous melatonin. The key...
KEY FINDING: Constant darkness after SCI in rats led to a significant increase in motor recovery and body weight compared to normal or constant light conditions.