Browse the latest research summaries in the field of immunology for spinal cord injury patients and caregivers.
Showing 11-20 of 620 results
Spinal Cord, 2024 • May 1, 2024
This qualitative study explored the knowledge, perceptions, and beliefs about UTIs among Veterans with neurogenic bladder (NB) to inform the development of person-centered interventions for improved U...
KEY FINDING: Participants showed knowledge gaps in UTI prevention, identifying specific UTI symptoms, and understanding antibiotic side effects.
Military Medical Research, 2023 • June 1, 2023
This review comprehensively examines the psychoneuroimmunoendocrinology (PNIE) of spinal cord injury (SCI), emphasizing the interconnectedness of neurological, immunological, and endocrine systems in ...
KEY FINDING: SCI involves both primary injury, which is often irreversible, and secondary injury, which can be delayed and potentially treatable. Understanding the pathophysiology of secondary damage is crucial for timely specialist intervention.
Brain, 2023 • June 28, 2023
The SCIentinel study prospectively assessed the impact of spinal cord injury (SCI) on the immune system, comparing SCI patients with varying injury levels and severities to vertebral fracture (VF) pat...
KEY FINDING: SCI patients, particularly those with high and complete injuries, exhibited significantly reduced mHLA-DR expression, indicating a suppressed immune state.
Frontiers in Immunology, 2023 • June 14, 2023
This study investigates the therapeutic mechanisms of transcranial intermittent theta-burst stimulation (iTBS) on nerve regeneration and functional recovery in rats with complete spinal cord transecti...
KEY FINDING: Transcranial iTBS reduces inflammation and neuronal apoptosis in the sensorimotor cortex (SMC) following spinal cord injury.
Frontiers in Molecular Neuroscience, 2023 • July 10, 2023
This review describes the changes in IL-10 and its receptors after spinal cord injury. It further elucidates the multiple neuroprotective effects and underlying mechanisms of IL-10 in the treatment of...
KEY FINDING: IL-10 exhibits anti-oxidative stress effects by enhancing mitochondrial homeostasis, decreasing lipid peroxidation, and inhibiting the production of peroxides and inflammatory cytokines after SCI.
Biomedicines, 2023 • July 7, 2023
This study examined the microbiological burden and catheter surface changes associated with short-term reuse. Catheter surface changes and the presence of antibiotic-resistant bacteria were evident fo...
KEY FINDING: Catheter swab cultures showed no growth after 48 h (47.8%), skin flora (28.9%), mixed flora (17.8%), or bacterial growth (5.5%).
Cureus, 2023 • July 7, 2023
This study evaluated the effectiveness of telerehabilitation for individuals with spinal cord injury (SCI) during the COVID-19 pandemic. The study found that telerehabilitation interventions were safe...
KEY FINDING: The self-care and mobility domains of the SCIM III in the intervention group compared to the control group, as determined through a between-group analysis, showed statistically significant differences.
Spinal Cord Series and Cases, 2023 • January 1, 2023
This paper reports two cases of spinal cord injury (SCI) resulting from pyogenic spinal infections (PSI) caused by Staphylococcus aureus, which complicated infected atopic eczema. Both patients were t...
KEY FINDING: Both patients developed spinal cord injuries as a result of pyogenic spinal infections (PSI) caused by Staphylococcus aureus originating from infected atopic eczema.
Spine Surg Relat Res, 2023 • January 17, 2023
This retrospective study examined the incidence and risk factors for pneumonia in patients with cervical spinal cord injury (CSCI) and complete motor paralysis. The study found that pneumonia occurred...
KEY FINDING: Pneumonia occurred in 36% of patients throughout the study period and in 20% after 30 days of hospitalization.
Fed Pract, 2023 • May 19, 2023
This retrospective study evaluated the frequency and characteristics of antibiotic allergies at a single SCI center. In this study, we evaluated the frequency and characteristics of antibiotic allergi...
KEY FINDING: Almost 30% of patients with SCI had a recorded allergy to at least 1 antibiotic. Almost 30% of patients with SCI had a recorded allergy to at least 1 antibiotic.