Browse the latest research summaries in the field of immunology for spinal cord injury patients and caregivers.
Showing 21-30 of 620 results
Journal of Neuroinflammation, 2023 • October 26, 2023
The study investigates the neuroendocrine mechanisms underlying SCI-induced immunodeficiency syndrome (SCI-IDS) using multitissue transcriptomic analysis in rats with high-level (T3) and low-level (T1...
KEY FINDING: High-level SCI leads to significant atrophy of immune organs like the thymus and spleen, while low-level SCI shows gradual recovery of these organs.
Arch Phys Med Rehabil, 2024 • January 1, 2024
This multicenter study evaluated the appropriateness of ASB and UTI management in patients with NB. It identified factors associated with inappropriate diagnosis and treatment to improve the quality o...
KEY FINDING: Nearly all ASB encounters had appropriate diagnosis (98%).
Scientific Reports, 2023 • October 11, 2023
This study aimed to understand the status of UTIs and bladder management in Chinese community-based SCI patients. The findings indicate a higher prevalence of UTIs in this population compared to devel...
KEY FINDING: The prevalence of UTIs in Chinese community SCI patients was 72.9%, higher than reported in developed countries.
PLOS ONE, 2023 • November 1, 2023
This qualitative study explored the perceptions, experiences, and beliefs regarding urinary tract infections (UTIs) in patients with neurogenic bladder (NB). It involved virtual focus groups with 23 V...
KEY FINDING: Caregivers play a crucial role in UTI management by enabling access to care, helping recognize symptoms, and aiding in understanding medical information.
Antibiotics, 2023 • November 2, 2023
This retrospective study evaluated the prevalence of bacterial pathogens, particularly MDR and ESBL-producing bacteria, in pressure ulcers of spinal cord injury patients. The study found that S. aureu...
KEY FINDING: Staphylococcus aureus was the most commonly isolated organism from ulcers, especially in sacral and gluteal regions.
J. Clin. Med., 2023 • November 15, 2023
This study investigates the impact of a wheelchair half marathon on the immune response of athletes with cervical (CSCI) and thoracic/lumber (SCI) spinal cord injuries, focusing on interleukin-1 recep...
KEY FINDING: IL-1ra levels were higher in SCI participants immediately after the race compared to CSCI participants. Additionally, IL-1ra increased in both groups one hour after the race.
Spinal Cord Series and Cases, 2023 • October 23, 2023
This case report presents the instance of a patient with a spinal cord injury developing an ITB pump infection involving Candida parapsilosis. The case highlights the diagnostic challenges in distingu...
KEY FINDING: A patient with SCI and an ITB pump developed a pump pocket infection with methicillin-sensitive Staphylococcus aureus, diphtheroids, and Candida parapsilosis.
Frontiers in Medicine, 2023 • November 17, 2023
This retrospective study aimed to investigate the occurrence rate of urinary tract infections (UTIs) in the early phase after performing intermittent catheterization (IC) and to explore the possible f...
KEY FINDING: UTI after performing IC is prevalent among people with SCI.
Int. J. Mol. Sci., 2023 • December 18, 2023
This study investigated the alteration of T lymphocytes in patients with chronic SCI over different years of evolution, revealing a progressive damage to the circulating T lymphocyte compartment. The ...
KEY FINDING: Chronic SCI patients show a significant reduction in circulating CD4+ and CD8+ T lymphocytes compared to healthy controls.
Top Spinal Cord Inj Rehabil, 2023 • January 1, 2023
This study investigated primary care antibiotic prescribing patterns for adults with SCI using linked health administrative and electronic medical records databases from 2013 to 2015. The study found ...
KEY FINDING: UTIs were the most common indication for antibiotic prescription, accounting for 59.8% of prescriptions.