Mental Health Research

KEY FINDING: In anhedonia-susceptible mice, the tissue levels of sEH were significantly increased in the medial prefrontal cortex (mPFC), hippocampus, spinal cord, liver, kidney, and gut.

KEY FINDING: Individuals with SCI are more likely to transition toward opioid use and dependence than toward less use or no use after their injury.

KEY FINDING: The frequency of suicidal ideation ranged from 4% to 67% within study samples.

KEY FINDING: 5-HT can either promote or inhibit pain depending on neural circuits, such as spinal pathways. It can also have excitatory or inhibitory functions in the same brain regions, depending on its receptors.

KEY FINDING: The total mean QoL score was 41.03 (SD: 12.92).

KEY FINDING: Remotely-delivered CBT shows small benefits for pain intensity and functional disability in adults experiencing chronic pain.

KEY FINDING: Prolonged neck flexion due to alcohol intoxication can lead to acute compressive cervical myelopathy.

KEY FINDING: Digital applications to promote the psychosocial health of individuals with SCI are an emerging field of research with many treatment approaches still to come.

KEY FINDING: Several studies suggest that psychedelics, particularly psilocybin and LSD, may reduce pain symptoms in chronic pain conditions such as phantom limb pain and cluster headaches.

KEY FINDING: Minocycline completely prevented the emergence of an 'affected' subgroup of rats displaying disrupted foraging behaviours after nerve injury.