Browse the latest research summaries in the field of mental health for spinal cord injury patients and caregivers.
Showing 221-230 of 290 results
eClinicalMedicine, 2024 • December 1, 2024
This meta-analysis used data from the CENTER-TBI and TRACK-TBI studies to explore whether polygenic risk scores (PRS) for PTSD and major depressive disorder (MDD) are associated with the development o...
KEY FINDING: PTSD-PRS was significantly associated with higher adjusted odds of PTSD in both cohorts, with a pooled odds ratio (OR) of 1.55 [95% confidence interval (CI) 1.30–1.84, p < 0.001].
Brain Sci., 2025 • February 14, 2025
Spinal cord injury (SCI) leads to secondary complications like gut dysbiosis (GD) and NLRP3 inflammasome activation, impacting mental health due to disrupted gut microbiome and inflammatory processes....
KEY FINDING: Gut dysbiosis (GD) and activation of the NLRP3 inflammasome are significant secondary complications after spinal cord injury (SCI), impacting mental health.
Neurobiology of Stress, 2024 • May 15, 2024
This study investigated whether coffee polyphenols could protect against early-life stress (ES)-induced cognitive deficits in male mice. ES was induced via limited nesting and bedding, and mice were g...
KEY FINDING: Coffee polyphenol supplementation early in life protected against ES-induced later life cognitive deficits, as evidenced by improved performance in object recognition and spatial memory tasks.
Frontiers in Neurology, 2015 • September 4, 2015
The autonomic nervous system (ANS) maintains internal homeostasis by interacting with brain structures, and its failure is commonly observed in neurological and neuropsychiatric disorders. This review...
KEY FINDING: Cardiovascular autonomic failure may negatively affect neurological disorders. There is evidence that ANS efficiency, cognitive performance, and brain activity are correlated, and baroreceptor stimulation reduces pain perception.
The Journal of Spinal Cord Medicine, 2015 • May 1, 2015
This study aimed to develop and validate a grief and loss item bank specific to individuals with spinal cord injury (SCI), addressing the limitations of existing measures focused on bereavement. The r...
KEY FINDING: The final calibrated item bank includes 17 items, demonstrating a unidimensional model and good measurement precision, indicating it's a robust tool.
Ann Rehabil Med, 2012 • December 1, 2012
The study investigated whether resilience could predict psychological distress in chronic SCI patients living in the community. The results indicated that while resilience is a possible predictor, hea...
KEY FINDING: Health-related quality of life (EQ-5D) was found to have a greater impact on psychological distress levels compared to resilience (CD-RISC).
The Journal of Spinal Cord Medicine, 2017 • September 1, 2017
This study aimed to identify the prevalence of adjustment disorders (AJD) among individuals with spinal cord injury (SCI) and to determine the pattern of defense styles used by this population. The st...
KEY FINDING: The prevalence of AJD was estimated to be 28% among individuals with SCI.
J Spinal Cord Med, 2009 • April 1, 2009
This study examined the factor structure of the PHQ-9 in a large sample of men and women with SCI to determine if the structure replicates across gender. Results supported a 1-factor structure of the ...
KEY FINDING: The 1-factor structure of the PHQ-9 was supported within and between sexes, indicating it can be used to compare overall depression scores between men and women with SCI.
The Journal of Spinal Cord Medicine, 2014 • January 1, 2014
The study examined sex differences in risk perceptions among individuals with spinal cord injury (SCI) and their relationship to community integration and participation. Women with SCI reported higher...
KEY FINDING: Women with SCI perceived more dangers on every item on the RISCI Scale compared to men.
Rehabil Psychol, 2017 • November 1, 2017
The study evaluated the frequency and appropriateness of test accommodations for individuals with neurological conditions completing the NIHTB-CB. Most participants (75%) completed the NIHTB-CB using ...
KEY FINDING: 75% of participants completed the NIHTB-CB using standard administration procedures.