Browse the latest research summaries in the field of musculoskeletal medicine for spinal cord injury patients and caregivers.
Showing 121-130 of 269 results
BioMed Research International, 2015 • May 19, 2015
This study investigated the molecular pathways involved in muscle remodeling after spinal cord injury (SCI) and treadmill training using a rat model. The researchers found that SCI altered protein ubi...
KEY FINDING: SCI led to rapid muscle weight loss, which was significantly reversed by treadmill training.
Top Spinal Cord Inj Rehabil, 2015 • January 1, 2015
Spinal cord injury (SCI) leads to rapid bone loss, resulting in severe osteoporosis and a significantly increased risk of fractures, which are associated with high complication rates and reduced quali...
KEY FINDING: SCI results in a 5- to 23-fold increase in fracture risk compared to able-bodied individuals.
PLoS ONE, 2016 • February 9, 2016
This systematic review assessed strategies to reduce muscle fatigue during FES exercise in individuals with SCI. It evaluated the methodological quality and effectiveness of various strategies. The re...
KEY FINDING: Optimizing electrode positioning can improve fatigue-resistance during FES.
Eur J Transl Myol - Basic Appl Myol, 2015 • January 1, 2015
The review examines the biology of muscle atrophy, particularly in the context of aging and mobility impairments, and how Functional Electrical Stimulation (FES) can aid in muscle recovery. The study ...
KEY FINDING: Activity maintains the motoneurons and the muscle fibers, evidenced by the different muscle fiber distribution between sedentary and active seniors.
Korean J Neurotrauma, 2015 • August 22, 2015
Leg swelling in paraplegic patients can be caused by heterotopic ossification (HO), deep vein thrombosis (DVT), fracture, or cellulitis, and these conditions can be difficult to distinguish clinically...
KEY FINDING: The patient's leg swelling was initially suspected to be DVT due to the diffuse nature of the swelling throughout the entire leg.
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2016 • January 15, 2016
This study aimed to investigate the effect of traditional Chinese kidney reinforcing and marrow‑beneficial medicine (KRMB) on the prevention and treatment of abnormal bone metabolism and osteoporosis ...
KEY FINDING: BMD expression in the SCI model group was significantly lower compared with the normal, sham + KRMB and normal + KRMB groups at 4, 6, 8 and 10 weeks.
Eur J Transl Myol, 2016 • April 1, 2016
The study investigates the survival of human muscle fibers after permanent denervation due to spinal cord injury (SCI) and the associated relocation of myonuclei. The findings indicate that severely a...
KEY FINDING: The percentage of muscle fibers with nuclear clumps increased significantly to 27 ± 9% between three to six years post-SCI.
Spinal Cord Series and Cases, 2015 • July 9, 2015
This case report highlights a rare instance of coracoclavicular ligament ossification in a patient with complete paraplegia following a clavicular fracture. The ossification led to a synostosis betwee...
KEY FINDING: The patient exhibited ossification of the coracoclavicular ligament, leading to synostosis between the clavicle and scapula, a rare occurrence in paraplegia patients.
Topics in Spinal Cord Injury Rehabilitation, 2016 • January 1, 2016
This case report describes a 22-year-old man with a T6 spinal cord injury who developed Gorham's disease in his right clavicle, presenting as shoulder pain during acute rehabilitation. The patient was...
KEY FINDING: A patient with traumatic spinal cord injury developed Gorham's disease in the distal right clavicle, presenting as shoulder pain.
J Neurotrauma, 2017 • November 1, 2017
This study aimed to determine if testosterone (TE) prevents bone deficits post-spinal cord injury (SCI) and if finasteride (FIN) is required for TE-induced skeletal preservation. The study found that ...
KEY FINDING: TE+FIN prevented the chronic cancellous bone deficits and LABC muscle loss in SCI animals without inducing prostate enlargement.