Browse the latest research summaries in the field of neuroimaging for spinal cord injury patients and caregivers.
Showing 51-60 of 90 results
Neuroradiology, 2017 • August 1, 2017
The study aimed to improve the specificity of DTI measurements in assessing SCI by using a subject-specific injury demarcation approach. This involved using DTI tractography to define regions relative...
KEY FINDING: DTI indices obtained from the IRRI region showed the highest specificity to impairment, demonstrating their strong potential as biomarkers for the SCI severity.
J Spinal Cord Med, 2007 • January 23, 2007
This study provides an evidence-based review of neuroimaging techniques used in spinal cord injury (SCI) clinical practice and research. The review assessed the role of various MRI techniques, Intraop...
KEY FINDING: MRI is the preferred imaging method for evaluating the spinal cord after injury, showing its effectiveness in identifying injury location and compression degree.
Ann Neurol, 2009 • October 1, 2009
The study investigates brainstem MRS as a surrogate marker for spinal cord axonal health in mice with virus-induced demyelination. Brainstem NAA levels correlate with axonal loss and remyelination in ...
KEY FINDING: Brainstem NAA concentrations decreased in both SJL and FVB mice at 90 days post-infection, indicating demyelination.
Multiple Sclerosis, 2010 • January 1, 2010
The study aimed to determine if diffusion tensor imaging (DTI) measures, radial diffusivity (RD) and axial diffusivity (AD), in the cortico-spinal tract (CST) can predict clinical recovery after a spi...
KEY FINDING: Lower baseline radial diffusivity (RD) in the cortico-spinal tract (CST) predicts better clinical outcomes in MS patients after a spinal cord relapse.
Brain, 2011 • May 1, 2011
This study investigated the impact of traumatic spinal cord injury (SCI) on structural integrity, cortical reorganization, and disability by assessing anatomical changes in the spinal cord and brain a...
KEY FINDING: Subjects with SCI had a 30% reduced cord area compared to controls, indicating spinal cord atrophy.
Neural Regeneration Research, 2018 • January 1, 2018
This study reports on a male patient with memory impairment who showed injury of the Papez circuit following TSCI and concomitant mild TBI. DTT revealed injury of the left thalamocortical tract and th...
KEY FINDING: The patient with TSCI and mild TBI showed memory impairment.
J Clin Neurol, 2018 • April 1, 2018
Diffusion-tensor imaging (DTI) is a noninvasive medical imaging tool used to investigate the structure of white matter. The signal contrast in DTI is generated by differences in the Brownian motion of...
KEY FINDING: DTI scalars like FA, AD, RD, MD, and MO can be correlated with clinical information to reveal abnormalities associated with neurological diseases.
NeuroImage: Clinical, 2018 • August 19, 2018
The study investigated early neurodegenerative changes following acute spinal cord injury (SCI) using quantitative MRI (qMRI) and assessed their predictive value for functional recovery. Results showe...
KEY FINDING: Early after SCI, there are decreases in the size of the spinal cord and changes in the cerebellum.
Frontiers in Neurology, 2018 • August 29, 2018
This study investigates the changes in the spinal cord after laminoplasty in patients with cervical myelopathy (CM) using diffusion tensor imaging (DTI). The results indicate that laminoplasty leads t...
KEY FINDING: CM patients showed significant changes in their postoperative diffusion metrics for the anterior ROIs compared with the preoperative measures both at and below the lesion level.
Neurology, 2019 • June 11, 2019
This study assessed the predictive value of midsagittal tissue bridges on MRI for sensorimotor recovery after cervical SCI. The width of dorsal tissue bridges correlated with sensory recovery and SEP ...
KEY FINDING: Greater width of dorsal midsagittal tissue bridges was associated with being sensory incomplete at 12 months, shorter SEP latencies, and greater SEP amplitudes.