Browse the latest research summaries in the field of neuroimaging for spinal cord injury patients and caregivers.
Showing 41-50 of 90 results
Annals of Neurology, 2015 • November 1, 2015
This study demonstrated progressive atrophic and microstructural changes across the sensory system in patients with subacute SCI. These structural changes, observed via MRI, were closely related to se...
KEY FINDING: Patients with SCI showed progressive degenerative changes in cervical cord and brain morphometry across the sensory system compared to controls.
NeuroImage, 2017 • June 29, 2017
The study introduces reliability masking, a novel outlier rejection technique for spinal cord DTI, to supplement existing artifact correction methods. Reliability masking, when added to registration a...
KEY FINDING: Adding reliability masking to established post-processing steps increased the statistical power of clinical findings by 4.7%.
Asian Journal of Neurosurgery, 2015 • July 1, 2015
This prospective study correlated clinical profiles and neurological outcomes with imaging findings in 25 acute SCI patients. Imaging features from radiographs, CT, and MRI were analyzed and correlate...
KEY FINDING: Patients with complete SCI had significantly more compression percentage, maximum canal compromise and maximum spinal cord compression at presentation.
PLOS ONE, 2015 • October 30, 2015
This study presents a unique longitudinal dataset of weekly rs-fMRI scans over 3.5 years to assess the reproducibility and temporal structure of rs-fMRI outcome measures. The research identifies 14 RS...
KEY FINDING: Resting-state functional MRI (rs-fMRI) outcome measures, specifically network spatial maps, temporal signal fluctuation magnitude, and between-network connectivity (BNC), showed high inter-session reproducibility.
Journal of NeuroEngineering and Rehabilitation, 2015 • November 6, 2015
The present study explored the test-retest reliability of motor performance and brain activation of a novel robot-aided experimental fMRI paradigm at the individual and group-level. The consistency of...
KEY FINDING: Reliability of motor performance was higher during passive than active movements, as seen in lower RMSE for passive movements.
PLOS ONE, 2016 • March 8, 2016
This study used resting-state fMRI to investigate changes in cortical sensorimotor connectivity following complete cervical spinal cord injury (SCI). Eleven patients with chronic cervical SCI and nine...
KEY FINDING: SCI patients showed decreased functional connectivity in motor and sensory cortical regions compared to controls, including ipsilateral, contralateral, and interhemispheric regions for left and right precentral ROIs.
Human Brain Mapping, 2016 • March 3, 2016
This study explored structural and functional changes in the spine and brain of SCI patients and their relationship to motor recovery, comparing patients with good and poor recovery to healthy control...
KEY FINDING: Poor recoverers had significantly decreased spinal cord area, cortical thickness in motor areas, and fractional anisotropy in the primary motor cortex compared to good recoverers.
Neural Plasticity, 2017 • February 1, 2017
The study aimed to determine if SCI could indirectly impair or reshape the white matter (WM) of the human brain and whether these changes correlate with injury severity, duration, or clinical performa...
KEY FINDING: SCI patients exhibited significant decreases in WM fractional anisotropy (FA) in several brain regions, including the left angular gyrus, right cerebellum, left precentral gyrus, left lateral occipital region, left superior longitudinal fasciculus, left supramarginal gyrus, and left postcentral gyrus.
Spinal Cord Series and Cases, 2017 • February 2, 2017
The study investigated the feasibility of using spinal cord fMRI to assess sexual responses in women with spinal cord injuries (SCI). fMRI responses during audiovisual stimulation, self-stimulation, a...
KEY FINDING: Spinal fMRI responses of the intermediolateral columns were found during audiovisual stimulation in both subjects with incomplete injuries, but not in the subject with a complete injury.
Yonsei Medical Journal, 2006 • January 1, 2006
This study investigates corticospinal tract compression due to hematoma in a patient with intracerebral hemorrhage using diffusion tensor tractography (DTT) and functional MRI (fMRI). The results show...
KEY FINDING: DTT showed the corticospinal tract in the affected hemisphere was displaced by the hematoma.