Browse the latest research summaries in the field of neurology for spinal cord injury patients and caregivers.
Showing 91-100 of 5,253 results
Acta Pharmaceutica Sinica B, 2023 • May 1, 2023
This study introduces a novel approach for treating CNS injuries, particularly stroke, by utilizing engineered extracellular vesicles (EVs) derived from M2 microglia. The EVs are modified with DA7R an...
KEY FINDING: Dual-EV nanocarriers target human umbilical vascular endothelial cells (HUVECs) and recruit NSCs in vitro.
iScience, 2023 • May 19, 2023
The study explores using a motor imagery (MI)-based brain-computer interface (BCI) to control a lower limb exoskeleton for motor recovery after neural injury, evaluated in able-bodied subjects and pat...
KEY FINDING: VR training did not reduce the BCI's effectiveness and may have improved it in some cases.
Front. Hum. Neurosci., 2023 • May 11, 2023
Neuromodulating the locomotor network through spinal cord electrical stimulation (SCES) is effective for restoring function in individuals with gait deficits. The existing literature suggests that com...
KEY FINDING: SCES can be utilized to restore gait in patients who have suffered from the effects of spinal cord injuries (SCI).
MOLECULAR MEDICINE REPORTS, 2023 • April 25, 2023
Porous GMSs were synthesized using a simple FGF10‑encapsulating procedure. More specifically, GMSs loaded with FGF10 were administered to SCI rats; FGF10 was then slowly released at the site of injury...
KEY FINDING: FGF10-GMS treatment led to superior outcomes in terms of neuroprotection, motor function and morphological recovery compared with FGF10 treatment.
Physiological Reports, 2023 • May 3, 2023
This study investigated the impact of electrode configuration and stimulation type (single pulses vs. trains) on spinally evoked motor response (sEMR) thresholds in lower limb muscles of non-SCI and S...
KEY FINDING: In non-SCI participants, the L1-midline electrode configuration required lower stimulation intensities compared to T11-midline and L1-ASIS configurations.
Neurorehabilitation and Neural Repair, 2023 • July 1, 2023
This study investigates the relationship between hand grasp types used at home by individuals with cervical SCI and their clinical assessment scores. Egocentric video was used to record and analyze ha...
KEY FINDING: Reliance on power grasp is positively correlated with clinical measures of independence and upper extremity motor function.
BMC Musculoskeletal Disorders, 2023 • July 5, 2023
This study constructed a prediction model based on clinical and MRI features to assess the probability of developing irreversible neurological dysfunction (IND) in patients with cervical spinal cord i...
KEY FINDING: Six features, including age, AIS grade, signal of spinal cord (SC), maximum canal compromise (MCC), intramedullary lesion length (IMLL), and specialized institution-based rehabilitation (SIBR), were included in the model.
Journal of Zhejiang University (Medical Sciences), 2023 • April 1, 2023
This study investigates the effectiveness of unstable surface torso training on lower limb motor function in patients with incomplete spinal cord injury. Eighty patients were randomly assigned to eith...
KEY FINDING: Unstable surface torso training significantly improved stride length, stride frequency, and comfortable walking speed compared to both pre-treatment and the stable surface training group.
Front. Neurol., 2023 • May 23, 2023
This study investigated the effects of plasma-synthesized polypyrrole/iodine (PPy/I) alone and in combination with swimming and enriched environment (SW/EE) rehabilitation on gene expression and locom...
KEY FINDING: PPy/I treatment upregulated genes related to developmental processes, biogenesis, synapses, and synaptic vesicle trafficking, suggesting a role in nerve regeneration and synaptic plasticity.
Eur J Transl Myol, 2023 • January 1, 2023
Long pulse stimulation in its application in everyday clinical practice still represents a challenge for many therapists and clinicians. A retrospective data analysis of n=128 patients, seen at the Sw...
KEY FINDING: From the 128 new patient cases, having been evaluated in 2022, 38% showed an upper motor neuron lesion, 49% a LMN lesion and 13% a combined lesion