Browse the latest research summaries in the field of neurology for spinal cord injury patients and caregivers.
Showing 5,091-5,100 of 5,253 results
Auton Neurosci, 2013 • December 1, 2013
The study examined the effects of cervical sympathetic trunk (CST) transection on sympathetic preganglionic neurons, focusing on changes in ChAT expression, soma size, and the presence of ATF3 in the ...
KEY FINDING: Significant decrease in soma volume and reduced soma expression of choline acetyltransferase (ChAT) in the intermediolateral cell column (IML) of T1 spinal cord were observed at 1 week.
Proc. Nati. Acad. Sci. USA, 1986 • April 1, 1986
The study demonstrates that axons in larval sea lampreys can regenerate across a spinal cord transection and form functional synapses. Fictive swimming induced in isolated spinal cords showed phase-lo...
KEY FINDING: Axons in the larval sea lamprey can regenerate across the site of a spinal cord transection and form functioning synapses with some of their normal target neurons.
Frontiers in Neurology, 2019 • March 26, 2019
This study demonstrates the feasibility of using functional ultrasound (fUS) imaging to monitor spinal cord hemodynamic responses to epidural electrical stimulation (SCS) in animal models. The researc...
KEY FINDING: fUS can detect spinal cord hemodynamic responses to epidural electrical stimulation (SCS) in both rat and swine models.
Spinal Cord Series and Cases, 2018 • April 5, 2018
This case report describes a rare instance of Brown-Sequard-Plus Syndrome (BSPS) and Brachial Plexopathy (BP) secondary to a gunshot wound. The patient's initial presentation with left hemibody weakne...
KEY FINDING: The patient had Brown-Sequard-Plus Syndrome (BSPS) at the T2 level along with left lower trunk Brachial Plexopathy (BP) after a gunshot wound.
NEURAL REGENERATION RESEARCH, 2025 • June 3, 2024
This study investigates the efficacy of combining Schwann cell (SC) transplantation with chondroitinase ABC (ChABC) to enhance neural repair and functional recovery following spinal cord injury (SCI) ...
KEY FINDING: Chondroitinase ABC (ChABC) treatment effectively degraded CSPGs, reduced glial response, and promoted the migration of grafted Schwann cells (SCs) in the injured spinal cord.
PLoS ONE, 2016 • June 29, 2016
The study aimed to determine whether spinal cord injury (SCI) is associated with a specific deficit in implicit motor sequence learning, using the serial reaction time (SRT) task to compare individual...
KEY FINDING: The SCI group did not show a decline in reaction time over the initial blocks of the SRT task, indicating impaired implicit learning.
Exp Neurol, 2007 • October 1, 2007
This study investigates the therapeutic potential of utilizing neurotrophin-transduced Schwann cells (SCs) to repair the injured spinal cord in a rat model of contusion. Schwann cells were transduced ...
KEY FINDING: D15A-secreting SC grafts exhibited 5-fold increases in graft volume, SC number and myelinated axon counts and a 3-fold increase in myelinated to unmyelinated (ensheathed) axon ratios.
Eur Spine J, 2009 • March 20, 2009
The study aimed to develop a quantitative skin impedance test to diagnose spinal cord injury (SCI), particularly in unconscious or non-cooperative patients. Skin impedance measurements were taken at s...
KEY FINDING: The artificial neural network (ANN) could classify traumatic SCI patients with a success rate of 73% when using skin impedance values.
Scientific Reports, 2024 • November 25, 2024
This study examined the potential of GnRH and GH treatments to promote neurotrophic and synaptic recovery in ovariectomized rats with thoracic SCI. The results showed that chronic administration of Gn...
KEY FINDING: GnRH and GH treatments upregulate the expression of neurotrophic and synaptogenic activity genes in rats with SCI.
Nutrients, 2022 • November 5, 2022
The gut microbiome is involved in nutrient metabolism and produces metabolites that, via the gut–brain axis, signal to the brain and influence cognition. Higher serum levels of propionic acid, a short-...
KEY FINDING: Higher serum levels of propionic acid were associated with increased odds of cognitive decline.