Browse the latest research summaries in the field of neurology for spinal cord injury patients and caregivers.
Showing 5,231-5,240 of 5,253 results
The Journal of Spinal Cord Medicine, 2016 • May 1, 2016
This study evaluated the impact of the 2013 revision of the ISNCSCI worksheet on classification performance by comparing it to the 2011 version. The results indicated that the 2013 revision led to a s...
KEY FINDING: The 2013 worksheet revision significantly improved overall classification performance compared to the 2011 revision.
Molecular Neurobiology, 2020 • August 30, 2019
This study investigates the regulation of CNS-specific PPARGC1A transcripts in human neuronal cell lines and a rat model of ischemia. The findings reveal that a GT repeat polymorphism and hypoxia infl...
KEY FINDING: A naturally occurring variable GT repeat polymorphism increases promoter activity in neuronal cell lines.
Rehabil Psychol, 2017 • November 1, 2017
This study examines the clinical utility of Motor-Free Composite scores that can be used in individuals with upper extremity motor functioning impairments. The Motor-Free scores are not a perfect matc...
KEY FINDING: Motor-Free composite scores are a reliable and valid way to examine overall and fluid cognition in individuals with upper extremity motor impairments.
J Neural Eng, 2012 • June 1, 2012
This study introduces an enhanced trajectory model for decoding neural signals, incorporating gaze-based target information and time-warping to account for variations in movement speed. The findings d...
KEY FINDING: Incorporating gaze-based target information significantly improves decoding accuracy compared to using EMG data alone, especially at simulated injury levels.
Prenatal Diagnosis, 2021 • January 1, 2021
This systematic review and meta-analysis evaluated the safety and efficacy of stem cell transplantation in animal models of MMC, finding beneficial effects on animal survival, defect coverage, and spi...
KEY FINDING: Intra-amniotic injection of allogeneic amniotic fluid mesenchymal stem cells (AF-MSCs) in the fetal rat model did not compromise fetal survival.
Surgical Neurology International, 2010 • October 20, 2010
This review summarizes recent advances in translational neuroscience, covering topics from spinal cord regeneration and stroke recovery to brain tumor treatment and epilepsy management. The authors hi...
KEY FINDING: Pten deletion enhances regenerative ability of adult corticospinal neurons following spinal cord injury in animal models.
JBC, 2012 • May 18, 2012
The neural cell adhesion molecule L1 plays crucial roles during development of the nervous system, such as neuronal migration and survival, axon outgrowth and fasciculation, and myelination, but it is...
KEY FINDING: L1 stimulation leads to the generation of a 70-kDa transmembrane fragment that is translocated to the nucleus.
Cell Mol Neurobiol, 2010 • July 14, 2010
This is a retraction note for an article originally published online on July 14, 2010, in Cellular and Molecular Neurobiology. The reason for the retraction is the duplication of a significant amount ...
KEY FINDING: The original article (DOI 10.1007/s10571-009-9449-4) has been retracted.
Frontiers in Aging Neuroscience, 2022 • December 7, 2022
This review synthesizes recent advances in understanding the immune response following spinal cord injury (SCI), highlighting the dual roles of various immune components in either promoting or hinderi...
KEY FINDING: Glial cells in the spinal cord, like astrocytes and microglia, are not just supportive cells but also key players in the immune response after SCI, influencing inflammation and tissue repair.
JCI Insight, 2021 • April 8, 2021
This study identifies Itga7-expressing muscle-resident glial cells that are activated by loss of neuromuscular junction (NMJ) integrity. Upon activation, muscle glial–derived progenies expressed neuro...
KEY FINDING: Muscle-resident glial cells, identified by Itga7 expression, are activated by nerve injury and express neurotrophic genes like Ngfr, Tnc and Gdnf.