Neurology Research

KEY FINDING: Motor function assessment indicated a relative recovery over time after spinal cord injury.

KEY FINDING: Subjects were able to safely complete at least 83% of the training sessions, demonstrating the feasibility of the program.

KEY FINDING: Transplantation of hTERT gene-transfected Schwann cells improved motor function in SCI rats between 1 and 4 weeks after model establishment.

KEY FINDING: Obesity is likely only one of several risk factors for IIH, as obesity is common while IIH is rare and affects genders differently.

KEY FINDING: Functional recovery in lampreys after spinal cord injury can occur through imperfect axonal regrowth and compensatory plasticity.

KEY FINDING: FMT significantly improved motor function recovery in SCI mice compared to those treated with antibiotics alone, as shown by BMS scoring, inclined plane test, and footprint analysis.

KEY FINDING: SKP-SCs survived long-term at the site of chronic SCI, integrated into the host spinal cord, and mitigated astroglial scar formation.

KEY FINDING: Addition of CSPGs to dorsal root ganglion (DRG) cultures resulted in a reduction of activated integrins and growth inhibition. By adding manganese to the cultures, both FAK phosphorylation and growth response was restored, indicating that integrin activation is sufficient to override the inhibitory effects of CSPGs.

KEY FINDING: Overexpression of constitutively active Rheb promoted survival of retinal ganglion cells in the acute (14 days) and chronic (21 and 42 days) stages of injury.

KEY FINDING: EPC-CM reduces inflammation by decreasing M1 macrophage activation and the release of pro-inflammatory cytokines.