Browse the latest research summaries in the field of neurorehabilitation for spinal cord injury patients and caregivers.
Showing 301-310 of 338 results
Exp Neurol, 2010 • September 1, 2010
This study investigated the use of peripheral nerve grafts (PNG) combined with chondroitinase ABC (ChABC) to promote axon regeneration after incomplete cervical spinal cord injury (SCI) in adult cats....
KEY FINDING: The peripheral nerve grafts survived in most animals, and thousands of myelinated axons were found within each graft.
JOURNAL OF NEUROTRAUMA, 2013 • February 1, 2013
This study provides a comprehensive quantitative description of motor deficits and compensations from the acute to the late chronic phase after C6 spinal cord hemisection. Permanent impairments were d...
KEY FINDING: A dramatic (50%), immediate and permanent loss of extensor force occurred in the forelimb but not in the hind limb of the injured side.
BioMed Research International, 2015 • January 5, 2015
The study investigated the therapeutic potential of skin-derived precursor cells (SKPs) in a rat model of cerebral ischemia, finding that SKPs transplantation improved behavioral measures of neurologi...
KEY FINDING: SKPs transplantation could improve the behavioral measures of neurological deficit.
Regenerative Therapy, 2025 • November 20, 2024
Spinal cord ischemia/reperfusion (IR) injury (SCII) can cause major autonomic, sensory, and motor damage and loss. The upregulation of Nrf2, a primary orchestrator of the oxidative stress response, ha...
KEY FINDING: Nrf2 and NFATC2 levels were reduced in PC12 cells after OGD/R treatment.
Applied Bionics and Biomechanics, 2018 • July 10, 2018
This retrospective study evaluated the feasibility and efficacy of Hybrid Assistive Limb (HAL) therapy in patients who underwent spine surgery. Nine patients with various spine disorders were included...
KEY FINDING: Walking speed improved significantly after HAL treatment. The speed during the 10MWT significantly improved from 64.1 ± 16.0 to 74.8 ± 10.8 m/min (P = 0 031).
Journal of NeuroEngineering and Rehabilitation, 2018 • May 10, 2018
Current SCI rehabilitation research focuses on technology-augmented physical interventions but faces challenges in clinical implementation due to feasibility, appropriateness, meaningfulness, and econ...
KEY FINDING: Strengths in SCI rehabilitation research include Feasibility (practical application), Appropriateness (alignment with motor learning), and Effectiveness (evaluation of clinical outcomes).
Scientific Reports, 2018 • August 10, 2018
This study evaluated the long-term efficacy and safety of aFGF in treating chronic SCI patients over a 48-month period. The aFGF was administered directly to the injured spinal cord during surgery and...
KEY FINDING: Significant improvements were observed in ASIA impairment scales, motor scores, pin prick, light touch, and FIM motor subtotal scores in both cervical and thoracolumbar SCI groups.
Neurorehabil Neural Repair, 2010 • January 1, 2010
The article discusses the importance of rehabilitation in conjunction with cellular transplantation for spinal cord injury (SCI). It highlights a study by Lima et al., which combined cell transplantat...
KEY FINDING: 75% of subjects developed electromyographic activity below their lesions.
J Neurol Phys Ther, 2009 • March 1, 2009
This systematic review evaluated the evidence supporting treadmill training with and without body weight support for children and young adults (under 21 years) with motor disabilities, including cereb...
KEY FINDING: Treadmill training is effective in accelerating walking development in children with Down syndrome.
Current Physical Medicine and Rehabilitation Reports, 2018 • November 15, 2018
Persons with spinal cord injuries (SCI) commonly experience individual risks and coalesced health hazards of the cardiometabolic syndrome (CMS). Evidence supports a therapeutic role for physical activ...
KEY FINDING: The CMS hazards of overweight/obesity, insulin resistance, hypertension, and dyslipidemia are strongly associated with physical deconditioning and are common after SCI.