Browse the latest research summaries in the field of oncology for spinal cord injury patients and caregivers.
Showing 31-40 of 144 results
JCI Insight, 2021 • March 8, 2021
Spinal cord injury (SCI) causes severe disability, and the current inability to restore function to the damaged spinal cord leads to lasting detrimental consequences to patients. Here, we developed a ...
KEY FINDING: MHC1 inhibits the activation of Cx43 hemichannels in both primary spinal astrocytes and astrocytes in situ.
The Journal of Spinal Cord Medicine, 2017 • March 1, 2017
This study addresses the rehabilitation of patients with spinal cord dysfunction (SCDys) caused by tumors. It includes a literature review, a survey of healthcare professionals, and expert opinions to...
KEY FINDING: Most respondents reported that people with benign tumors were routinely admitted for rehabilitation but only a smaller percentage reported that people with malignant tumors were routinely admitted.
Clinical Medicine, 2014 • May 1, 2014
Metastatic spinal cord compression (MSCC) is a critical complication of cancer requiring urgent attention. It is caused by compression of the spinal cord due to metastases, leading to neurological def...
KEY FINDING: MSCC is an oncological emergency requiring prompt recognition and intervention to prevent irreversible neurological damage.
Medicine, 2015 • February 1, 2015
This case report presents two cases of spinal neurilemmoma in a 29-year-old man and an 11-year-old boy, highlighting the clinical and radiographic features of this rare condition. Both patients underw...
KEY FINDING: Intraspinal neurilemmoma, though rare, should be considered when diagnosing spinal cord compression.
Pain Research and Management, 2022 • July 8, 2022
This study explored the relationship between pain, bone metastasis, and cytokine expression in cancer patients treated with external radiation therapy. The research aimed to identify specific cytokine...
KEY FINDING: Radiotherapy significantly improved pain scores and quality of life in cancer patients with bone metastasis.
Phys Med Rehabil Clin N Am, 2017 • February 1, 2017
Spinal tumors can be classified into extradural, intradural extramedullary and intradural intramedullary tumors. Management of spinal tumors varies according to the stability of the spine, neurologica...
KEY FINDING: Localized spine pain is the most common symptom in patients with epidural spinal cord compression at the time of diagnosis.
British Journal of Cancer, 2006 • January 24, 2006
This retrospective audit assessed the care of 174 patients with MSCC at a UK cancer centre over a 12-month period, revealing shortcomings in pain assessment, patient mobility, and rehabilitation plann...
KEY FINDING: The common primary tumor diagnoses were lung (29%), prostate (19%), and breast (13%).
Acta Orthopaedica, 2017 • April 1, 2017
This study evaluated the outcomes of surgical treatment for metastatic spinal cord compression (MSCC) as the initial manifestation of malignancy (IMM) in 69 patients. The primary outcomes assessed wer...
KEY FINDING: Postoperative survival depends on the type of primary tumor, with prostate cancer and myeloma showing the longest survival.
Orthopaedic Surgery, 2017 • May 1, 2017
This case report describes a 31-year-old pregnant woman with a giant cell tumor (GCT) in her thoracic spine. The patient underwent cesarean section followed by tumor resection and spinal fusion, with ...
KEY FINDING: GCT in the mobile spine during pregnancy is rare, with only eight cases with detailed clinical data previously reported.
Cancer Management and Research, 2018 • January 1, 2018
This report describes a case of cervical intramedullary diffuse glioma resection assisted by intraoperative MRI (ioMRI). The ioMRI system was designed for multioperation rooms. After initial resection...
KEY FINDING: ioMRI detected residual tumor tissues indistinguishable under the surgical microscope.