Browse the latest research summaries in the field of oncology for spinal cord injury patients and caregivers.
Showing 41-50 of 144 results
Ann Rehabil Med, 2013 • April 1, 2013
This case report describes a rare instance of a giant cell tumor (GCT) in the T2 vertebra of an adolescent female, leading to spinal cord injury and subsequent neurological deficits. The patient under...
KEY FINDING: The patient presented with upper back pain and sudden weakness of the lower extremities due to a GCT on the T2 vertebra.
The Journal of Spinal Cord Medicine, 2014 • January 1, 2014
This case report describes a 42-year-old female with T-cell ALL who developed dorsal column myelopathy following intrathecal chemotherapy. The patient experienced ascending lower limb numbness and bal...
KEY FINDING: The patient developed ascending, symmetric circumferential numbness in both lower limbs within 24 hours of intrathecal chemotherapy.
Cell Death and Disease, 2025 • January 29, 2025
The study demonstrates that the nuclear orphan receptor NR2F6 represses the expression of the activating receptor NKp46, an established key player in NK cell-mediated cytotoxicity during infection and...
KEY FINDING: NR2F6 represses the expression of the activating receptor NKp46, a key player in NK cell-mediated cytotoxicity.
Molecular Oncology, 2021 • January 24, 2021
This study benchmarks HLA genotyping on TCGA data using multiple tools to generate reliable HLA genotyping results. It finds that HLA class I genotyping is generally better than class II genotyping, w...
KEY FINDING: POLY-SOLVER, OptiType, and xHLA show high accuracy in HLA class I genotyping, with accuracies of 0.954, 0.949, and 0.937, respectively.
AGING, 2021 • May 17, 2021
This study identified nine prognostic immune genes in extranodal diffuse large B-cell lymphoma (EN DLBCL) and established a multivariate predictive model based on these genes, demonstrating that patie...
KEY FINDING: Nine prognostic immune genes were identified in EN DLBCL, including IFNA21, KIR2DL1, MUCL1, SFTPA2, MX1, USP18, CCL1, IGLV1-36, and GLP1R.
BIOENGINEERED, 2021 • August 23, 2021
This study identifies alternative splicing events associated with bladder cancer bone metastasis and constructs a predictive model for prognosis. The research proposes a regulatory mechanism involving...
KEY FINDING: Alternative splicing events (ASEs) are associated with the occurrence and progression of bladder cancer and have a relationship with its prognosis.
Cancers, 2022 • January 29, 2022
The urinary bladder is an immunogenic organ. The occurrence of BC permanently alters the immune landscape of the bladder. Immunizing therapies, either as bladder instillation or as intravenously or or...
KEY FINDING: Durvalumab plus Oportuzumab monatox, Pembrolizumab, and Nadofaragene firadenovec (NF) show complete response (CR) rates of 41.6%, 40.6%, and 59.6% after 3 months.
Nanomaterials, 2022 • March 30, 2022
This review highlights the potential of lipid-based nanomaterials in addressing bone complications, particularly bone metastasis, by offering targeted drug delivery and improved therapeutic efficacy. ...
KEY FINDING: Lipid-based nanocarriers can be modified with bisphosphonates to enhance their affinity for bone, allowing for improved drug delivery to targeted areas within the bone structure.
J Neurosurg Case Lessons, 2021 • December 20, 2021
This case report describes an extremely rare instance of intradural extramedullary (IDEM) metastasis of parotid acinic cell carcinoma (ACC) in a 79-year-old male with a 29-year history of the disease....
KEY FINDING: The patient presented with progressive cervical myelopathy 29 years after initial diagnosis of parotid ACC, indicating a rare late recurrence and metastasis.
Cancers, 2022 • July 23, 2022
The purpose of this study was to retrospectively analyze the diagnostic accuracy of magnetic resonance imaging (MRI) examinations of the scrotum in comparison with standard ultrasound (US) and histopa...
KEY FINDING: MRI shows good sensitivity and specificity for the estimation of testicular tumors in this collective.