Browse the latest research summaries in the field of orthopedics for spinal cord injury patients and caregivers.
Showing 301-310 of 352 results
Frontiers in Bioengineering and Biotechnology, 2022 • May 13, 2022
This editorial highlights the growing need for effective strategies to repair musculoskeletal tissue, especially tendon injuries and chronic tendinopathies. The special issue of Frontiers in Bioengine...
KEY FINDING: Pathological inflammation differs from reparative inflammation, and immunomodulatory therapies could be effective if timed correctly.
Journal of Orthopaedic Surgery and Research, 2025 • January 16, 2025
This study investigated the impact of simulated overload and microgravity on intervertebral disc degeneration in rabbits. The researchers focused on the expression of MMP1, MMP3, and TIMP1. The study ...
KEY FINDING: MMP1 and MMP3 expression increased significantly in experimental groups compared to controls. The increase correlated with longer exposure to simulated overload and microgravity.
Journal of Inflammation Research, 2016 • September 22, 2016
This study aimed to determine if BMP-7 contributes to improved bone regeneration in nonunion therapy by modulation of angiogenic and inflammatory cytokine expression patterns. The study found that BMP...
KEY FINDING: BMP-7 increases VEGF levels, which promote angiogenesis, essential for bone healing.
Journal of Orthopaedic Surgery and Research, 2018 • December 4, 2018
This study evaluated the efficacy of a modified vacuum-assisted closure (VAC) for treating early postoperative spinal wound infections. The results show that the size of the wound after treatment with...
KEY FINDING: Wound size significantly decreased after 1 week of modified VAC treatment.
Reumatologia, 2017 • April 1, 2017
Cervical spine involvement is common in rheumatoid arthritis (RA) and can lead to various types of instability, potentially causing neurological complications. Early identification of these instabilit...
KEY FINDING: Plain radiographs are a common initial imaging method due to their availability and low cost, particularly for assessing atlanto-axial joint anomalies using functional radiographs in flexion and extension.
BMC Surgery, 2023 • June 3, 2023
This study aimed to investigate the risk factors for adjacent vertebral compression fractures (AVCF) after vertebroplasty and to establish a clinical prediction model. The study identified low bone ma...
KEY FINDING: Low bone mass density (BMD) is an independent risk factor for AVCF after vertebroplasty.
Spine Deformity, 2025 • September 4, 2024
This case report describes a rare instance of delayed neurological deficit six years after adolescent idiopathic scoliosis (AIS) surgery, caused by a medially misplaced thoracic pedicle screw followin...
KEY FINDING: A medially misplaced T8 pedicle screw, previously asymptomatic, caused a delayed neurological deficit six years after scoliosis surgery following a motor vehicle collision.
Journal of Orthopaedic Surgery and Research, 2024 • December 1, 2024
This retrospective study analyzed 90 adult patients with severe rigid scoliosis (SRS) who underwent posterior column osteotomy (PCO) and fusion to identify risk factors for postoperative coronal imbal...
KEY FINDING: Preoperative coronal imbalance (CIB+) is significantly associated with postoperative CIB [OR = 12.414 (95% CI: 2.228, 69.162), P = 0.004].
Scientific Reports, 2017 • March 8, 2017
This study aimed to determine the effect of a high-glucose diet on Achilles tendon healing in a rat model. The results indicated that a high-glucose diet significantly affects tendon healing after inj...
KEY FINDING: A high-glucose diet increased tendon repair tissue thickness and stiffness after 2 weeks in rats.
The Journal of Spinal Cord Medicine, 2019 • July 1, 2019
This pilot study examined personal and wheelchair factors related to increased pretibial skin pressures in elite wheelchair racers during static and dynamic conditions. Increased kneeling plate angle ...
KEY FINDING: Increased kneeling plate angle was moderately associated with dynamic pressures, meaning a more vertical angle leads to higher pressure during racing.