Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.
Showing 291-300 of 555 results
Scientific Reports, 2016 • January 6, 2016
This study shows distinct association of below-level NP with structural changes of the spinal cord and brain after SCI. In individuals with paraplegia, the reduction in SCA was associated with below-l...
KEY FINDING: Individuals with SCI exhibited decreased cord area, reduced grey matter (GM) volumes in anterior cingulate cortex (ACC), left insula, left secondary somatosensory cortex, bilateral thalamus, and decreased white matter volumes in pyramids and left internal capsule.
Annals of Neurology, 2016 • April 1, 2016
This randomized, double-blind, placebo-controlled study evaluated the analgesic effect of botulinum toxin type A (BTX-A) on neuropathic pain in patients with spinal cord injury (SCI). The study found ...
KEY FINDING: BTX-A significantly reduced pain intensity compared to placebo at both 4 and 8 weeks post-injection, as measured by the Visual Analogue Scale (VAS).
Cochrane Database of Systematic Reviews, 2017 • January 1, 2017
This overview of Cochrane Reviews examined the effectiveness and safety of physical activity and exercise for chronic pain in adults. The review included 21 Cochrane Reviews encompassing various chron...
KEY FINDING: Several reviews noted favourable results from exercise on pain severity, but the results were inconsistent across interventions and follow-up periods.
Rehabil Psychol, 2016 • February 1, 2016
The study examined the independent contributions of vulnerability and resilience factors to pain-related outcomes in individuals with chronic pain and physical disabilities. Results indicated that res...
KEY FINDING: Both resilience and vulnerability factors significantly contribute to pain outcomes.
The Journal of Spinal Cord Medicine, 2018 • May 1, 2018
This study developed and validated the SCI-QOL Pain Interference item bank and the SCI-QOL Pain Behavior scale, which are optimized for individuals with SCI. The measures were developed using qualitat...
KEY FINDING: The SCI-QOL Pain Interference item bank and the SCI-QOL Pain Behavior scale demonstrated robust psychometric properties.
Journal of Pain Research, 2016 • June 15, 2016
This study explored the relationship between pain relief and improvement in function among patients with SCI-associated NeP. Pain reduction is likely associated with improvement in several different d...
KEY FINDING: Greater functional improvements were generally achieved at higher levels of clinically significant pain reduction.
BMC Neurology, 2017 • March 15, 2017
The study aimed to evaluate the measurement properties of painDETECT (PD-Q) using Rasch analysis to determine its suitability as an outcome measure for neuropathic pain (NeP). The analysis involved da...
KEY FINDING: PD-Q demonstrated fit to the Rasch model after adjustments of scoring categories for four items, and omission of the time course and radiating questions.
The Journal of Spinal Cord Medicine, 2018 • January 1, 2018
This case report demonstrates the feasibility and potential benefits of using percutaneous PNS to treat chronic shoulder pain in an individual with SCI. The subject experienced a reduction in pain and...
KEY FINDING: The subject experienced a 44% reduction in worst pain one week after the end of treatment, as measured by the BPI-SF3 scale.
Toxins, 2015 • July 10, 2015
This study demonstrated that repetitive injections of DBV into the Joksamli acupuncture point during the induction phase (one to five days after SCI) of below-level neuropathic pain significantly prod...
KEY FINDING: Repetitive DBV stimulation during the induction period suppressed pain behavior in the ipsilateral hind paw.
Drug Design, Development and Therapy, 2020 • December 4, 2020
This study investigates the effect of sanguinarine (SG) on chronic constriction injury (CCI)-induced neuropathic pain (NP) in rats. SG is a natural plant medicine known for its anti-inflammatory and n...
KEY FINDING: Sanguinarine (SG) treatment increased paw withdrawal mechanical threshold (PWT) and thermal withdrawal latency (TWL) in CCI rats, indicating reduced mechanical sensitivity and heat hypersensitivity.