Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.
Showing 551-555 of 555 results
Annals of Rehabilitation Medicine, 2013 • December 1, 2013
This case report presents a rare instance of supernumerary phantom limbs (SPL) and phantom limb pain in a patient with complete spinal cord injury (SCI). The patient experienced the sensation of an ad...
KEY FINDING: A patient with complete spinal cord injury experienced supernumerary phantom limbs (SPL) and associated phantom limb pain, a rare occurrence.
Molecular Pain, 2006 • August 17, 2006
This study demonstrates that peripheral nerve injury induces changes in the excitability and sodium channel expression in the VPL nucleus of the thalamus. Specifically, the expression of Nav1.3 sodium...
KEY FINDING: Peripheral nerve injury (CCI) leads to increased firing rates of VPL neurons in response to peripheral stimuli.
British Journal of Pharmacology, 2018 • January 1, 2018
This study investigates the analgesic effects of ASP3662, a novel 11β-HSD1 inhibitor, in rat models of neuropathic and dysfunctional pain. ASP3662 is a potent, selective, and CNS-penetrable inhibitor ...
KEY FINDING: ASP3662 effectively inhibits 11β-HSD1 in humans, mice, and rats, demonstrating selectivity over 11β-HSD2 and showing no significant impact on other enzymes, transporters, and receptors.
Spinal Cord Series and Cases, 2018 • October 16, 2018
This study followed up with individuals with SCI who had previously completed a 3-month anti-inflammatory diet to assess their dietary compliance and the persistence of benefits related to mood and ne...
KEY FINDING: Diet compliance significantly decreased from 92.6% at 3 months to 43.0% at the 1-year follow-up (p < 0.01).
Annals of Rehabilitation Medicine, 2014 • June 1, 2014
This study characterized neuropathic pain in SCI patients using the Baron classification. The most common pain characteristic was pricking pain, followed by electrical pain and numbness. The study fou...
KEY FINDING: Pricking pain was the most common pain characteristic among SCI patients with neuropathic pain, followed by electrical pain and numbness.