Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.
Showing 61-70 of 555 results
Journal of Neuroinflammation, 2024 • August 22, 2024
This study aimed to explore the roles of oligodendrocytes and their interactions with other glial cells in neuropathic pain (NP) development using a chronic constriction injury (CCI) model in mice and...
KEY FINDING: Neuropathic pain peaked on day 7 after chronic constriction injury in mice, concurrent with myelin lesions in both the spinal cord and sciatic nerve.
Trials, 2024 • January 1, 2024
This study is a double-blind, randomized controlled trial designed to assess the impact of aerobic exercise on neuropathic pain and quality of life in individuals with chronic paraplegia. Participants...
KEY FINDING: The trial aims to provide new knowledge about the effectiveness of aerobic exercise in improving neuropathic pain and QoL in individuals with chronic paraplegia.
Interventional Pain Medicine, 2024 • June 5, 2024
This retrospective study investigates the safety of cervical transforaminal epidural steroid injections (TFESIs) using non-particulate steroids over a 17-year period at an academic institution. The st...
KEY FINDING: No catastrophic complications (spinal cord injury, stroke, death or other) were reported in 6241 cervical TFESIs performed between 2004 and 2021.
Interventional Pain Medicine, 2023 • April 25, 2023
This case report describes a rare instance of immediate post-operative paraplegia following spinal cord stimulator implantation with a paddle electrode in a 70-year-old male. Despite prompt interventi...
KEY FINDING: A 70-year-old male developed immediate post-operative incomplete paraplegia following spinal cord stimulator implantation with a thoracic paddle electrode.
Interventional Pain Medicine, 2023 • April 27, 2023
This case report describes the successful use of spinal cord stimulation (SCS) to treat pain-induced autonomic dysreflexia (AD) in a 46-year-old female with chronic incomplete traumatic quadriplegia. ...
KEY FINDING: The patient experienced a significant reduction in AD episodes following SCS implantation, with a reported 75% improvement in AD symptoms three months after the procedure.
Interventional Pain Medicine, 2023 • January 2, 2023
This case report describes an 83-year-old male who developed anterior spinal artery syndrome (ASAS) nine days after undergoing kyphoplasty for a T8 vertebral compression fracture. The ASAS was caused ...
KEY FINDING: A rare case of delayed-onset ASAS occurred nine days after kyphoplasty, caused by retropulsion of a bone fragment from a refractured vertebral body.
Interventional Pain Medicine, 2023 • November 2, 2023
This case report describes a patient who suffered a spinal cord injury following a cervical epidural injection. The patient had a history of prior cervical surgery and received the injection for uncon...
KEY FINDING: A patient developed a spinal cord injury (SCI) after an interlaminar cervical epidural injection (CEI).
Spinal Cord, 2024 • September 12, 2024
This manuscript describes the rationale and components of the EEG neurofeedback intervention designed for individuals with SCI neuropathic pain and intended for home-based implementation. The EEG neur...
KEY FINDING: EEG neurofeedback may offer clinically meaningful benefits in pain intensity and pain interference for individuals with chronic pain.
CNS Neurosci Ther, 2024 • January 1, 2024
This study aimed to determine if the combined application of CLP290 and bumetanide maximizes the improvement of neuropathic pain following spinal cord injury (SCI) and to elucidate its potential molec...
KEY FINDING: The combined treatment of CLP290 and bumetanide provided the most significant improvement in restoring Rate-Dependent Depression (RDD) levels.
Brain Communications, 2024 • August 19, 2024
This study demonstrates that intraspinal microstimulation (ISMS) of the ventral horn can simultaneously reduce neuropathic pain and improve movement in a rat model of spinal cord injury. The study fou...
KEY FINDING: Intraspinal microstimulation (ISMS) in the ventral horn reduces transmission through nociceptive specific and wide dynamic range neurons in response to pain-related sensory feedback.