Browse the latest research summaries in the field of physiology for spinal cord injury patients and caregivers.
Showing 231-240 of 292 results
J Physiol, 2010 • June 2, 2010
This study investigated the sprouting capacity of lumbar motoneurons in normal and hemisected spinal cords of rats, focusing on the effectiveness of motor unit enlargement in compensating for partial ...
KEY FINDING: Enlargement of intact motor units (MUs) by sprouting was effective in compensating for up to 80% loss of innervation.
Thorax, 1972 • January 1, 1972
The study investigates the phrenic nerve and diaphragmatic plexus in gerbils, focusing on nerve fiber distribution, spinal cord connections, and structural features. It also compares findings with tho...
KEY FINDING: The phrenic nucleus in gerbils is more extensive than in other species, spanning from the second to the sixth cervical segment of the spinal cord.
Frontiers in Physiology, 2014 • February 25, 2014
This review focuses on the role pannexins play in inflammation-induced regeneration in various tissues, highlighting their involvement in cell death, differentiation, and tissue repair. Pannexins, par...
KEY FINDING: Pannexin-1 (Panx1) channels function as an integral component of the P2X/P2Y purinergic signaling pathway and is arguably the major contributor to pathophysiological ATP release.
Stem Cell Reports, 2014 • March 11, 2014
The study demonstrates the existence of intrinsically active neurons (IANs) in pluripotent stem cell-derived neuronal networks, using mouse embryonic stem cells. These IANs are functionally integrated...
KEY FINDING: Pluripotent stem cell-derived neuronal networks contain intrinsically active neurons (IANs) that remain active after blocking fast synaptic communication.
Cell Calcium, 2014 • July 1, 2014
This study shows that muscle cell precursors in regenerating tissues exhibit spontaneous calcium transients after tail amputation. These calcium transients are mediated by ryanodine receptor-operated ...
KEY FINDING: Muscle cell precursors in regenerating tails exhibit spontaneous calcium transients.
Neural Regen Res, 2013 • November 1, 2013
This study monitored spinal cord ischemia-reperfusion injury in rabbits using somatosensory evoked potential detection technology. The results showed that the somatosensory evoked potential latency wa...
KEY FINDING: Somatosensory evoked potential latency was significantly prolonged during spinal cord ischemia, reflecting the degree of ischemic injury.
J Neurol Surg B, 2014 • June 26, 2014
The olfactory mucosa is a specialized sensory organ for smell, and a better understanding of its cellular biology and physiology is necessary to appreciate experiments using animal models. The olfacto...
KEY FINDING: The human olfactory mucosa appears slightly yellow and lacks the distinctive hue seen in rodents, concentrated in the posterosuperior nasal cavity near the cribriform plate.
The Journal of Neuroscience, 1989 • April 1, 1989
This study investigated the role of the medullary pacemaker nucleus (PMN) in electroreceptor tuning plasticity in Sternopygus macrurus. The researchers examined hormone-mediated shifts and the develop...
KEY FINDING: The PMN is not necessary for the hormone-mediated shift of electroreceptor tuning.
J. Physiol., 1979 • January 1, 1979
Denervation of one cutaneous-pectoris muscle of the frog induces the formation of new synapses in the intact innervated muscle on the opposite side. The formation of the new synapses in the intact mus...
KEY FINDING: Denervation of one cutaneous-pectoris muscle induces the formation of new synapses in the intact innervated muscle on the opposite side.
Eur J Neurol, 2025 • January 1, 2025
CHEPs revealed distinct patterns of spinal cord impairment independent of structural T2-positive lesions, which were associated with measures of cord motion. CHEPs thus provide valuable complementary...
KEY FINDING: Abnormal CHEPs were present in T2-positive DCM (C6:41%; C8:32%; T4:24%) and T2-negative DCM (C6:35%; C8:54%; T4:26%).