Physiology Research

KEY FINDING: Tendons have a more complex vascular network than previously believed, with vessels entering from musculo-tendineous junctions, bone insertion sites, and the paratenon.

KEY FINDING: After nerve injury, the excitability changes associated with primary afferent depolarization were significantly less than in control animals.

KEY FINDING: Paralyzed muscles transform to faster myosin types, increasing contractile speeds and fatigue.

KEY FINDING: New tendinous connections formed after tendon transfer, often near original insertion sites, potentially compromising the mechanical action of the transferred muscle.

KEY FINDING: The traditional view that reflexes return in a caudo-rostral sequence (from the tail to the head) after spinal shock may not be accurate.

KEY FINDING: Reflex response times (S/R times) were shorter when the stimulated nerve had a larger innervation field, especially between the 15th and 17th segmental nerves.

KEY FINDING: The modified protocol significantly improves the yield of viable, intact myofibers compared to previous methods, achieving approximately 2300–3100 myofibers from two FDB muscles of a single mouse.

KEY FINDING: Damage ratios were negatively correlated with distance walked in 6 minutes, average daily strides, and maximum plantarflexion torque.

KEY FINDING: Long-term electrical stimulation training of the paralyzed soleus muscle resulted in rapid and prolonged improvement in fatigue resistance.

KEY FINDING: FES treatment significantly increased muscle fiber diameter in denervated muscles compared to untreated muscles. The fiber size increase was accompanied by a reduction in connective and adipose tissues.