Browse the latest research summaries in the field of research methodology & design for spinal cord injury patients and caregivers.
Showing 581-590 of 607 results
Top Spinal Cord Inj Rehabil, 2018 • January 1, 2018
This study investigates factors associated with loss to follow-up (FU) in a large cohort of individuals with spinal cord injury (SCI) using data from the National Spinal Cord Injury Database. The rese...
KEY FINDING: Loss to FU rates were 23.1% at post-injury year 1 and 32.9% at year 5, exceeding 40% between years 20 and 35.
JOURNAL OF NEUROTRAUMA, 2011 • August 1, 2011
This systematic review assessed the psychometric properties of various disability assessment tools used in spinal cord injury (SCI) patients. The study aimed to identify the most reliable, valid, and ...
KEY FINDING: Criterion validity was not examined due to the lack a gold standard for the assessment of disability.
Scientific Reports, 2019 • June 13, 2019
The study aimed to validate a fetal lamb model for spina bifida (SB) research, comparing two surgical models (with and without myelotomy) to normal lambs. The myelotomy model best phenocopied the anat...
KEY FINDING: The myelotomy model best replicates the anatomy, pathophysiology, and symptoms of non-cystic spina bifida (SB).
JOURNAL OF NEUROTRAUMA, 2018 • April 1, 2018
The paper critically appraises a 2014 Cochrane review on intermittent catheterization, which concluded that there was no convincing evidence that UTI incidence is affected by catheterization technique...
KEY FINDING: The authors identified concerns with the Cochrane review related to data selection, extraction, symptomatic UTI definition, and data analysis.
Frontiers in Molecular Neuroscience, 2022 • September 7, 2022
This review focuses on the unique advantages of using zebrafish larvae as a model for studying spinal cord regeneration, emphasizing their optical transparency, simple anatomy, and complex locomotor b...
KEY FINDING: Spinal cord regeneration in zebrafish larvae is distinct from development, with injury-dependent responses such as immune cell infiltration and glial bridge formation.
J Spinal Cord Med, 2008 • January 1, 2008
Breaking bad news regarding prognosis for significant motor recovery following a neurologically complete SCI is difficult for the spinal cord medicine specialist. The article provides physicians with ...
KEY FINDING: Communicating the prognosis effectively is crucial for patients with SCI to understand their condition and foster hope for the future.
Top Spinal Cord Inj Rehabil, 2017 • January 1, 2017
This study validated an algorithm for identifying persons with non-traumatic spinal cord dysfunction (NTSCD) using administrative health data in Alberta, Canada. The algorithm demonstrated high sensit...
KEY FINDING: The algorithm has high sensitivity (97%) and positive predictive value (PPV) (92%) for identifying NTSCD cases.
J Spinal Cord Med, 2007 • January 1, 2007
The purpose of this study is to report the results of rater agreement for the International Standards for Neurological Classification of Spinal Cord Injury (ISCSCI) motor and sensory scores before and...
KEY FINDING: Training improved rater agreement of summed motor scores (MS) from ICC ¼0.809 to 0.862 and discrimination scores from ICC¼0.786 to 0.892.
Spinal Cord Series and Cases, 2018 • October 16, 2018
The International Spinal Cord Injury (SCI) Urodynamic Basic Data Set (version 2.0) aims to standardize the collection and reporting of urodynamic data for individuals with SCI. The revised dataset inc...
KEY FINDING: The "Detrusor function" variable was divided into "Detrusor function during filling cystometry" and "Detrusor function during voiding" to provide more specific information.
Leukemia, 2016 • January 29, 2016
This study by the European Research Initiative on CLL (ERIC) identified and validated a flow-cytometric approach to reliably quantitate CLL cells to the level of 0.0010% (10 −5). A parallel analysis o...
KEY FINDING: A six-marker flow cytometry panel (CD19, CD20, CD5, CD43, CD79b, and CD81) was identified as reliable and convenient for identifying typical CLL cells.