Research Methodology & Design Research

KEY FINDING: Combining scratch injury with kainate treatment resulted in the most significant glial scarring, indicated by increased expression of GFAP, vimentin, CSPG, ROCK, and EphA4.

KEY FINDING: FFT allows for an objective quantification of photomicrographs based on morphology, which reduces the subjectivity associated with pixel-intensity methods.

KEY FINDING: Seven discipline-specific SCI rehabilitation taxonomies were developed.

KEY FINDING: SCOs effectively model spinal cord morphogenesis, offering insights into the intricate processes of neural tube formation and regional specification.

KEY FINDING: Patients with complete sensory-motor lesions have very limited chances of regaining walking function, and if they do, they are often 'limited ambulators'.

KEY FINDING: Men had 62%–96% greater shoulder torques than women, indicating significantly higher upper body strength.

KEY FINDING: Publications in this field have grown rapidly in the past 2 decades and are expected to keep increasing.

KEY FINDING: HGF-induced changes in gene expression were indicative of nerve regeneration and anti-inflammatory effects, in agreement with our earlier and simpler analysis of these RNA-seq data that then mostly neglected the time course of expression

KEY FINDING: The patient presented with myelomalacia located in the posterior funiculus at C3 in addition to the anterior horn from C2 to C4.

KEY FINDING: Stem cells can promote remyelination, neurite outgrowth, and axonal elongation after spinal cord injury.