Browse the latest research summaries in the field of surgery for spinal cord injury patients and caregivers.
Showing 381-390 of 390 results
Neural Regeneration Research, 2016 • August 1, 2016
This study used high-resolution aCGH to identify pathogenic CNVs in samples from patients with typical TCS. Our findings suggest an association between certain CNVs and nervous system disease. Ours st...
KEY FINDING: Array-based comparative genomic hybridization can be used to diagnose tethered spinal cord syndrome.
J Spinal Cord Med, 2005 • July 1, 2005
This paper presents two cases of individuals with spinal cord injury (SCI) who experienced late complications from thoracolumbar fusion instrumentation, specifically displaced hooks and protruding rod...
KEY FINDING: Both individuals experienced back pain from proximal hook displacement, without neurologic decline.
The Journal of Spinal Cord Medicine, 2011 • April 1, 2011
This study reports on a series of eight patients who underwent nerve allograft transplantation for brachial plexus injuries. The goal was to assess the safety and efficacy of using cadaveric or living...
KEY FINDING: Seven out of eight patients showed signs of nerve regeneration after allograft transplantation, indicated by return of sensory and motor function or a migrating Tinel’s sign.
J Korean Neurosurg Soc, 2010 • January 1, 2010
The study aimed to investigate the molecular biologic characteristics of primary and recurrent herniated discs to understand the similarities and differences in their gene expression profiles. The res...
KEY FINDING: mRNA gene expression of recurrent disc cells showed increased expression of aggrecan, type I collagen, type II collagen, Sox-9, osteocalcin, and alkaline phosphatase compared to primary herniated lumbar disc cells.
SpringerPlus, 2014 • June 24, 2014
This study aimed to establish a standardized laparoscopic approach for pudendal nerve localization and electrode implantation in pigs. The laparoscopic technique proved feasible, reproducible, and saf...
KEY FINDING: Laparoscopic access to the pudendal nerve was successfully established in all pigs.
Spinal Cord Series and Cases, 2018 • February 19, 2018
This case report presents a 34-year-old male, 12 years post-cervical spinal cord injury, who underwent nerve transfer surgery to restore hand function. The surgery involved transferring a branch of th...
KEY FINDING: Nerve transfers can successfully restore volitional hand function even more than 10 years following SCI.
Cureus, 2025 • January 10, 2025
This study assessed microcirculatory changes in cervical SCI patients with neurogenic shock using NIRS and VOT, finding a high prevalence of microcirculatory alterations. The study linked these microc...
KEY FINDING: The prevalence of microcirculatory alterations was high (92%) in patients with SCI and neurogenic shock, with 47% still exhibiting alterations at day 7.
Prenatal Diagnosis, 2021 • January 1, 2021
This systematic review and meta-analysis evaluated the safety and efficacy of stem cell transplantation in animal models of MMC, finding beneficial effects on animal survival, defect coverage, and spi...
KEY FINDING: Intra-amniotic injection of allogeneic amniotic fluid mesenchymal stem cells (AF-MSCs) in the fetal rat model did not compromise fetal survival.
Surgical Neurology International, 2010 • October 20, 2010
This review summarizes recent advances in translational neuroscience, covering topics from spinal cord regeneration and stroke recovery to brain tumor treatment and epilepsy management. The authors hi...
KEY FINDING: Pten deletion enhances regenerative ability of adult corticospinal neurons following spinal cord injury in animal models.
Cureus, 2022 • May 30, 2022
Spinal cord injuries (SCI) initiate a complex pathological process, necessitating a comprehensive understanding of intrinsic procedures for ensuring optimal treatment and recovery conditions. Vascular...
KEY FINDING: Endogenous angiogenesis, while triggered by SCI and ischemia, is frequently inadequate to address the progressive local ischemia and cell death.