Urology Research

KEY FINDING: After hUC-MSC treatment, the patient could move her toes three weeks after the first intrathecal and intravenous implantation.

KEY FINDING: The success rate for the surgical procedure and maintaining the implanted devices intact is approximately 80%.

KEY FINDING: Transection of L7 dorsal roots was necessary for significant reduction of squat-and-void postures after sacral root transection.

KEY FINDING: Early SNM improved bladder function with better capacities and lower detrusor pressures at voiding and avoided the emergence of detrusor sphincter dyssynergia (DSD).

KEY FINDING: Transected ventral and dorsal roots in the sacral spine can be repaired and are capable of functionally reinnervating the urinary bladder.

KEY FINDING: Avulsion injuries led to urinary retention, absence of bladder contractions and EUS EMG activation, increased bladder size, and retrograde death of autonomic and motoneurons.

KEY FINDING: DiI-labeled neurons were mainly in the left ventral horn from L3 to L5, with some being ChAT-positive.

KEY FINDING: The implanted series showed reflex bladder contractions with a significantly shortened urine expulsion phase compared to sham-operated controls.

KEY FINDING: VRA injury leads to overall thinning of the bladder wall, reduced thickness of the lamina propria and smooth muscle, and increased thickness of the bladder epithelium.

KEY FINDING: Zebrafish foxj1a, but not foxj1b, was rapidly induced in response to epithelial distension and stretch, kidney cyst formation, acute kidney injury, and crush injury in spinal cord cells.