Browse our collection of 11,526 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 4,011-4,020 of 11,526 results
Stem Cell Res Ther, 2021 • September 27, 2021
This study aimed to investigate the therapeutic effects of basic fibroblast growth factor (bFGF)-overexpressing human umbilical cord-derived mesenchymal stem cells (HUCMSCs) in mice with completely tr...
KEY FINDING: bFGF-overexpressing HUCMSCs met the standards and safety of MSCs for clinic use, indicating their potential for clinical translation.
International Journal of Environmental Research and Public Health, 2021 • September 27, 2021
This study pooled longitudinal data from five cohort studies of pediatric injury survivors (5–17 years) at baseline, 1-, 4-, 6-, 12-, and 24- months (n = 2334). HRQoL outcomes over time for children an...
KEY FINDING: Mean EQ-5D post-injury did not return to baseline level (0.95) by 24 months (0.88) and was lower for females over time (−0.04, 95%CI −0.05, −0.02).
J Neurosurg Case Lessons, 2021 • September 27, 2021
This case report presents an instance of adult-onset cervicothoracic split cord malformation (SCM) in a 60-year-old female who initially presented with nonspecific symptoms, leading to a delayed diagn...
KEY FINDING: Adult-onset presentation of cervicothoracic SCM is extremely rare, often leading to delayed diagnosis due to nonspecific symptoms.
Cureus, 2021 • September 26, 2021
Ischemia-reperfusion injury is a rare but serious complication following spinal decompression surgeries, potentially leading to paralysis due to oxidative damage and inflammation. This case report pre...
KEY FINDING: The patient developed diffuse cord edema and postoperative quadriplegia after undergoing posterior cervical laminectomy for severe cervical stenosis.
Journal of Immunology Research, 2021 • September 24, 2021
This study investigates the impact of various stress conditions on the release of extracellular vesicles (EVs) by Trypanosoma cruzi trypomastigotes. The research examines how factors like temperature,...
KEY FINDING: Low temperatures (4°C) and acidic conditions (pH 5.0) increase EV release by Trypanosoma cruzi trypomastigotes.
The EMBO Journal, 2021 • September 24, 2021
The study reveals a conserved developmental map of the human telencephalon, highlighting the temporal cell fate transition from neuroectoderm (NE) to radial glial cells (RGs) to intermediate progenito...
KEY FINDING: Dorsal and ventral telencephalons share common developmental programs during neurogenesis, following a conserved trajectory from radial glial cells (RGs) to intermediate progenitor cells (IPCs_div) and then to early neuroblasts (eNBs).
Behav Brain Res, 2021 • September 24, 2021
This study investigates the impact of combining robot-assisted gait training (RAGT) and skilled reach training on locomotor recovery in rats with spinal cord injury (SCI). The findings indicate that w...
KEY FINDING: Robot-assisted gait training (RAGT) alone can partially reduce deficits in overground locomotion following spinal cord injury in rats.
Journal of Rehabilitation Medicine, 2021 • September 24, 2021
This study investigated the multidimensionality of acceptance of SCI using a split-sample PCA and CFA approach. A 4-dimensional model of acceptance with the sub-dimensions “Accepting Reality”, “Value ...
KEY FINDING: Acceptance of SCI is a multidimensional construct with 4 sub-dimensions: “Accepting Reality”, “Value Change”, “Letting Go of Control”, and “Behavioural Engagement”.
Spinal Cord Series and Cases, 2021 • September 24, 2021
This qualitative study explored the experiences of individuals with incomplete SCI participating in high-intensity walking exercise after discharge from subacute inpatient rehabilitation. The study id...
KEY FINDING: Participants were motivated by hope for improvement and a sense of security from supervision but faced challenges due to bodily impairments.
Frontiers in Rehabilitation Sciences, 2021 • September 24, 2021
Transcutaneous Spinal Cord Stimulation (TSCS) has been shown to enhance the excitability of spinal neural circuits. This excitation is associated with enhanced voluntary performance in patients with i...
KEY FINDING: TSCS, both in single sessions and repeated applications, is associated with improved standing postural control, gait kinematics, and upper extremity function.