Browse our collection of 11,526 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 4,021-4,030 of 11,526 results
Journal of Extracellular Vesicles, 2021 • September 23, 2021
This study introduces a QCM-I and AFM-based protocol for characterizing EVs by elasticity and surface markers, tailored for reproducibility and integration in existing labs. The method utilizes specif...
KEY FINDING: The study established QCM as a sensitive label-free method for characterizing clinically approved umbilical cord MSC-EVs, detecting EVs via specific EV and MSC markers.
Spinal Cord, 2021 • September 23, 2021
This study examined the relationships between resilience, access to resources, and concerns related to the COVID-19 pandemic on the overall and mental health of individuals with SCI. The study found t...
KEY FINDING: Incomplete injury, concern about medical rationing, medical supply disruption, and social isolation predicted a greater perceived impact of the pandemic on overall heath.
BMC Fam Pract, 2021 • September 22, 2021
The study examined the first point of contact for health problems related to spinal cord injury (SCI), comparing general practitioners (GPs) and SCI-specialists. Results showed that age, language, dis...
KEY FINDING: Persons with SCI who initially contact an SCI-specialist have more secondary conditions and use health-care services more often.
The Journal of Neuroscience, 2021 • September 22, 2021
This study investigates the role of hyperpolarization-activated, cyclic nucleotide-gated (HCN) ion channels in oligodendrocytes, focusing on their impact on myelin sheath length. The researchers found...
KEY FINDING: Oligodendrocytes abundantly express functional, predominantly HCN2 subunit-containing ion channels, which retain key pharmacological and biophysical features.
Scientific Reports, 2021 • September 22, 2021
This study aimed to characterize the evolution of the cutaneous microbiota of pressure ulcers (PU) in a spinal cord injury (SCI) cohort, analyzing tissue biopsies at baseline and 28 days using 16S rRN...
KEY FINDING: Wounds with a 'Stagnated/Worsened' evolution had a significantly higher relative abundance of Anaerococcus and Finegoldia at baseline (D0).
BMC Psychol, 2021 • September 22, 2021
The study investigated how individuals with SCI learn self-care skills during inpatient rehabilitation, focusing on the role of the rehabilitation team. Participants emphasized learning through experi...
KEY FINDING: Learning self-care skills was mainly achieved through experience, challenging oneself, and utilizing opportunities provided by the rehabilitation team.
Nature Communications, 2021 • September 21, 2021
This study investigates fibrotic scarring in human pathological tissue and corresponding mouse models of penetrating and non-penetrating spinal cord injury, traumatic brain injury, ischemic stroke, mu...
KEY FINDING: The study demonstrates that type A pericytes are the primary source of scar-forming fibroblasts across various CNS lesions in mice, including spinal cord injury, traumatic brain injury, ischemic stroke, and multiple sclerosis.
Frontiers in Cellular Neuroscience, 2021 • September 21, 2021
The review summarizes how non-invasive respiratory treatments can be used to harness neuroplastic potential and enhance long-term recovery after cervical spinal cord injury (SCI). Specific attention i...
KEY FINDING: Spontaneous respiratory neuroplasticity has been reported in both clinical and experimental studies, serving as an excellent example of how the nervous system adapts to injury in order to maintain a vital, physiological function.
Scientific Reports, 2021 • September 20, 2021
The study investigated the role of ankle muscle co-contraction on postural stability in individuals with incomplete spinal cord injury (iSCI) compared to able-bodied (AB) individuals. The iSCI group d...
KEY FINDING: Individuals with iSCI exhibited more co-contractions compared to able-bodied individuals during quiet standing with eyes open and closed.
Spinal Cord Series and Cases, 2021 • September 19, 2021
Dual lesion SCI is a rare condition involving two distinct regions of injury to the spinal cord, posing unique challenges in evaluation, management, and classification. This case report presents a pat...
KEY FINDING: The patient initially presented with a T6 ASIA Impairment Scale (AIS) B paraplegia due to a gunshot wound to the T5 vertebra.