Browse our collection of 11,526 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 4,031-4,040 of 11,526 results
J Cell Mol Med, 2021 • September 19, 2021
This study investigates the inhibitory effect of EV-miRNA-22 on the inflammatory response in spinal cord injury (SCI) in rats. The researchers loaded mesenchymal stem cells (MSCs)-EV with miRNA-22...
KEY FINDING: EV-miRNA-22 could inhibit the occurrence of pyroptosis in microglia, suppress the cell membrane pore opening, and inhibit the release of inflammatory factors and the expression of GSDMD.
Spinal Cord Series and Cases, 2021 • September 19, 2021
This case report investigates the feasibility and tolerance of RobUST-intervention, a robotic postural training, to improve standing in an ambulatory individual with spinal cord injury. The study foun...
KEY FINDING: The participant showed improved balance in specific standing positions, particularly when vision was limited.
Neural Regeneration Research, 2022 • September 17, 2021
This study aimed to evaluate the impact of time-to-enrollment in chronic SCI clinical trials by analyzing data from ClinicalTrials.gov and individual patient data from regenerative intervention trials...
KEY FINDING: The majority of chronic SCI trials in ClinicalTrials.gov do not restrict the maximum post-injury time for trial eligibility.
Neural Plasticity, 2021 • September 17, 2021
This study aimed to determine the frequency and associated risk factors of asymmetrical prominent veins (APV) in patients with acute ischemic stroke (AIS) within 12 hours of symptom onset. The study f...
KEY FINDING: The frequency of high APV (volume ≥10 mL) was 46.05% in patients with AIS within 12 hours of symptom onset.
Spinal Cord Series and Cases, 2021 • September 17, 2021
This case report describes a 20-year-old wheelchair athlete who developed segmental spinal myoclonus secondary to acute on chronic cervical myelopathy following routine intubation. The patient's sympt...
KEY FINDING: Segmental spinal myoclonus can be a presenting symptom of acute cervical myelopathy, even in younger patients with congenital spinal abnormalities.
Scientific Reports, 2021 • September 16, 2021
This study introduces a thermosensitive injectable gel loaded with Decorin for treating spinal cord injuries in rats. The gel facilitates sustained Decorin release, reduces cavitation, promotes ECM de...
KEY FINDING: The BC/FB gel formed within 1 minute at 37 °C and released Decorin in a sustained manner for up to 30 days in vitro.
Spinal Cord Series and Cases, 2021 • September 16, 2021
This retrospective study examined the therapeutic content of an interdisciplinary follow-up clinic for individuals with spinal cord injury (SCI), focusing on the prevention and management of secondary...
KEY FINDING: Participants received an average of 3.9 recommendations per visit, largely focused on prevention and physical health issues.
Pain Ther, 2021 • September 15, 2021
The study investigated the impact of pedicle screw insertion trajectory on disc height recovery after fusion surgery for degenerative lumbar spondylolisthesis (DLS). The results suggest that the Cauda...
KEY FINDING: Changes in disc height (DH) were significantly associated with lower pedicle screw angle.
Biomaterials Research, 2021 • September 15, 2021
This study investigates a 3D-printed PLA cage/Biogel scaffold as a carrier for BMP-2 to enhance bone regeneration in rat calvarial defect and ectopic ossification models. The scaffold was designed for...
KEY FINDING: The in vitro results showed the cage/Biogel scaffold released BMP-2 with an initial burst release and followed by a sustained slow-release pattern, maintaining its osteoinductivity for at least 14 days.
Spinal Cord Series and Cases, 2021 • September 15, 2021
This case report describes a rare presentation of neurosarcoidosis in a 29-year-old female with spinal extradural and intramedullary involvement without pulmonary involvement, highlighting the diagnos...
KEY FINDING: The patient presented with progressive myelopathy secondary to multifocal spinal extradural neurosarcoidosis with spinal cord compression and without pulmonary involvement.