Browse our collection of 11,526 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 4,051-4,060 of 11,526 results
Brain Sciences, 2021 • September 12, 2021
Neuropathic pain following spinal cord injuries is difficult to treat. VR offers an alternative by providing illusory or reality-like experiences. VR modulates body ownership and agency, increasing pa...
KEY FINDING: VR can modulate the sense of ownership of the whole body or single body parts by altering the congruity of multisensory information.
Spinal Cord, 2022 • September 11, 2021
This cross-sectional study explored the prevalence of comorbidities and secondary health conditions (SHCs) in the Finnish population with spinal cord injury (SCI) using data from the Finnish Spinal Co...
KEY FINDING: High blood pressure/hypertension (38%), back problems (28%), and high cholesterol (22%) were the most common comorbidities among the Finnish population with SCI.
Spinal Cord, 2022 • September 9, 2021
The study investigated the effects of rTMS on lower limb muscle strength and gait function in SCI patients. Twenty participants were randomized to receive rTMS or sham stimulation for four weeks, alon...
KEY FINDING: High-frequency rTMS may increase long-term training-induced recovery of lower limb muscle strength following SCI.
International Journal of Environmental Research and Public Health, 2021 • September 9, 2021
This systematic review provides an updated qualitative review of walking ability outcome measures in SCI, considering diverse factors involving walking function and their limitations. Thirteen walking...
KEY FINDING: Thirteen different walking ability outcome measures were identified and grouped into categories, including multivariate walking metrics, spatiotemporal-related walking/balance measures, categorical measures of ambulation and balance measures.
BMJ Open, 2021 • September 9, 2021
This prospective one-armed multi-centre proof-of-concept study investigates the safety, feasibility and therapeutic potential of mesencephalic locomotor region (MLR)-deep brain stimulation (DBS) ...
KEY FINDING: MLR-DBS can modulate the activity of spared reticulospinal fibres that bypass the site of injury and reintegrate quiescent sublesional circuits.
BMJ Open, 2021 • September 9, 2021
This protocol outlines a single-arm proof-of-concept trial (PROMPT-SCI) to evaluate the feasibility and benefits of early activity-based therapy (ABT) in the form of in-bed leg cycling for patients wi...
KEY FINDING: The primary goal is to determine if early in-bed leg cycling can increase the likelihood of patients recovering independent walking ability 6 months after their injury.
J Nanobiotechnol, 2021 • September 8, 2021
The strategy of using a combination of scaffold-based physical and biochemical cues to repair spinal cord injury (SCI) has shown promising results. In summary, we prepared an electroactive hydro-gel s...
KEY FINDING: The developed hydrogel exhibits outstanding electrical conductance upon ES, with continuous release of NGF for at least 24 days.
Frontiers in Neurology, 2021 • September 8, 2021
This study quantitatively assessed muscle mechanical and electrical properties in cervical spinal cord injury (CSCI) survivors using myotonometry and electrical impedance myography (EIM). The findings...
KEY FINDING: Freq, stiffness, and maxForce of the SCI group were significantly lower than those of the healthy control, indicating muscle atrophy.
J NeuroEngineering Rehabil, 2021 • September 8, 2021
This study aimed to determine which kinematic variables obtained during a drinking task were associated with three clinical assessments of upper extremity functioning (ARAT, SHFT, ISCI-Hand) in people...
KEY FINDING: Wrist angle combined with movement time or smoothness explained a large portion of the variance in ARAT and SHFT scores.
Clin Exp Immunol, 2021 • September 7, 2021
This review explores the proregenerative roles of Tregs in zebrafish and mammals, highlighting the FoxP3-dependent immunosuppressive function of Tregs in zebrafish as a useful model for future researc...
KEY FINDING: Zebrafish possess two FOXP3 orthologs, foxp3a and foxp3b, potentially serving a redundant role in Treg formation and activity.