Latest Research Summaries
Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 4,121-4,130 of 12,052 results
Spinal epidural arteriovenous fistula with improved sphincter impairment detected by intraoperative neurophysiological monitoring
Surgical Neurology International, 2022 • August 26, 2022
This case report describes a 77-year-old woman with a spinal epidural arteriovenous fistula (SEAVF) who presented with progressive motor weakness, numbness, and urinary and fecal incontinence. The pat...
KEY FINDING: A patient with SEAVF experienced improved sphincter function 1.5 years after endovascular embolization.
Successful treatment of focal hand dystonia after cervical whiplash injury by thalamotomy
Surgical Neurology International, 2022 • August 26, 2022
This case report describes a 39-year-old woman who developed focal hand dystonia after a whiplash injury. She underwent Vo thalamotomy and later Vo-Vim thalamotomy after recurrence of dystonia. The pa...
KEY FINDING: The patient experienced significant improvement in hand function and was able to maintain her normal physical routine for eight years following the second surgery (Vo-Vim thalamotomy).
Spinal cord stimulation for neuropathic pain following traumatic spinal cord injury: a case report
Spinal Cord Series and Cases, 2022 • August 26, 2022
This case report describes the successful use of spinal cord stimulation (SCS) to treat neuropathic pain in a 30-year-old man with an incomplete spinal cord injury (SCI) resulting from gunshot wounds ...
KEY FINDING: A 30-year-old male with a T12 AIS B incomplete spinal cord injury secondary to multiple GSW experienced severe bilateral lower extremity dysesthesias and muscle spasms.
The antimicrobial peptide cathelicidin drives development of experimental autoimmune encephalomyelitis in mice by affecting Th17 differentiation
PLoS Biology, 2022 • August 26, 2022
This study demonstrates that the antimicrobial peptide cathelicidin drives severe autoimmune disease in the mouse model of MS. Exposure of CD4+ T cells in the draining lymph node to neutrophil-derived...
KEY FINDING: Cathelicidin is expressed by multiple cell types in lymphoid organs and the central nervous system during EAE, including neutrophils, endothelial cells and microglia/macrophages.
Combined treatment with medial unicompartmental knee arthroplasty and anterior cruciate ligament reconstruction is effective on long‑term follow‑up
Knee Surgery, Sports Traumatology, Arthroscopy, 2023 • August 25, 2022
The purpose of the present study was to evaluate the long-term outcome of combined medial unicompartmental knee arthroplasty (UKA) and anterior cruciate ligament reconstruction (ACLR). UKA combined wi...
KEY FINDING: UKA combined with ACLR is an effective therapeutic option with good outcome and return to sport rate on the long-term.
Autonomic Dysreflexia following Spinal Cord Injury
AJNS, 2022 • August 25, 2022
Autonomic dysreflexia (AD) is a potentially life-threatening condition that arises from spinal cord injuries at or above the T6 level, characterized by sudden increases in blood pressure due to unmodu...
KEY FINDING: AD is triggered by afferent sensory stimulation leading to unmodulated reflex sympathetic hyperactivity, resulting in a sudden increase in blood pressure.
Advances in Biomimetic Photoelectrocatalytic Reduction of Carbon Dioxide
Advanced Science, 2022 • August 25, 2022
This review explores biomimetic strategies for constructing photoelectrocatalytic (PEC) interfaces to mimic natural photosynthesis for CO2 conversion. It discusses various biomimetic PEC interfaces, i...
KEY FINDING: Biomimetic PEC interfaces can be constructed using metal cocatalysts/semiconductors, small molecules/semiconductors, molecular catalysts/semiconductors, MOFs/semiconductors, and microorganisms/semiconductors.
A Localized Materials-Based Strategy to Non-Virally Deliver Chondroitinase ABC mRNA Improves Hindlimb Function in a Rat Spinal Cord Injury Model
Adv. Healthcare Mater., 2022 • August 25, 2022
The study addresses the challenge of delivering therapeutic proteins, specifically ChABC, to spinal cord injuries (SCIs) due to their instability. It explores a non-viral mRNA-based method using miner...
KEY FINDING: MCM-mediated mRNA delivery is an efficient non-viral gene delivery method in primary neural cells in vitro and enabled localized transgene expression in the glial scar in vivo.
Qualitative analysis of perceived motivators and barriers to exercise in individuals with spinal cord injury enrolled in an exercise study
Spinal Cord Series and Cases, 2022 • August 25, 2022
This study examines the motivators and barriers to exercise among individuals with SCI enrolled in an internet-based exercise intervention program. Participants reported that improving physical health...
KEY FINDING: The leading reasons reported for enrolling were to improve their physical health (69%), function (61%), and attitude (59%).
Editorial: Women in science: Interventions for rehabilitation
Frontiers in Rehabilitation Sciences, 2022 • August 25, 2022
This editorial introduces a special issue of Frontiers in Rehabilitation Sciences focused on "Women in Science: Interventions for Rehabilitation." The editorial highlights the underrepresentation of w...
KEY FINDING: Women researchers are underrepresented in science, with fewer than 30% globally.