Browse our collection of 11,526 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 4,111-4,120 of 11,526 results
Photoacoustics, 2021 • August 26, 2021
This study investigates the feasibility of using multi-wavelength photoacoustic (MWPA) analysis to detect collagen in bone as a biomarker for bone health assessment, focusing on the wavelength range o...
KEY FINDING: The study successfully demonstrated the feasibility of using multi-wavelength photoacoustic (MWPA) analysis for detecting collagen content in bone.
Frontiers in Cellular Neuroscience, 2021 • August 26, 2021
This study investigates the mechanisms behind spontaneous locomotor recovery after spinal cord hemisection in rats. The researchers found that significant hindlimb locomotor recovery occurs four weeks...
KEY FINDING: Spontaneous hindlimb locomotor recovery occurs in rats four weeks after spinal cord hemisection.
Oxidative Medicine and Cellular Longevity, 2021 • August 26, 2021
This study investigates the therapeutic potential of microglia-derived exosomes (MG-Exos) in treating spinal cord injury (SCI). The results demonstrate that MG-Exos can reduce oxidative stress, promot...
KEY FINDING: MG-Exo treatment significantly decreased the level of oxidative stress (ROS) in vitro and in vivo when cells were exposed to H2O2-induced oxidative stress.
Frontiers in Neurorobotics, 2021 • August 26, 2021
This study aimed to determine if training with the HAL® Robot Suit could improve physiological gait in SCI patients in addition to functional parameters. The results showed that participants improved ...
KEY FINDING: Participants showed improved physiological parameters such as phases of gait cycle, accompanied by significant improvement in all spatiotemporal and gait phase parameters.
JRM-CC, 2021 • August 26, 2021
SAC are rare lesions that may present with a constellation of neurological symptoms: paraesthesia, neuropathic pain, paresis and gait disturbances, just like a (progressive) spinal cord injury due to ...
KEY FINDING: Spinal arachnoid cysts may present with a heterogeneous clinical picture.
Cells, 2021 • August 25, 2021
Experimental in vivo models are of critical importance for exploring the potential clinical relevance of mechanistic findings and therapeutic innovations. Here, we discuss injury (axotomy) of dorsal ro...
KEY FINDING: Restoration of functions that are lost following dorsal root injury requires that injured dorsal root axons are able to extend axons through a non-permissive environment, which is rapidly building up at the DREZ.
International Journal of Environmental Research and Public Health, 2021 • August 25, 2021
This pilot study investigated the immediate effect of VR in reducing neuropathic pain (NP) in people with spinal cord injury (SCI). Eight individuals with chronic NP after SCI underwent consecutive ex...
KEY FINDING: Short-term exposure to both scenery and somatic VR environments resulted in a significant reduction in neuropathic pain intensity in people with spinal cord injury.
Stem Cells International, 2021 • August 24, 2021
This study investigates the use of umbilical cord mesenchymal stem cells (UC-MSCs) combined with hydroxyapatite (HA) scaffolds for treating vertebral bone defects caused by spondylitis tuberculosis. T...
KEY FINDING: The study found increased bone formation at the defect site over six months, with 75-100% of the bone area showing formation. This suggests the stem cell and scaffold combination supports bone regeneration.
Journal of Neuroinflammation, 2021 • August 24, 2021
This study investigates the neuroprotective effects of tauroursodeoxycholic acid (TUDCA) in a mouse model of spinal cord injury (SCI). The results demonstrate that TUDCA treatment can alleviate second...
KEY FINDING: TUDCA reduces oxidative stress and protects cortical neurons in vitro, demonstrated by reduced ROS generation and LDH release.
EMBO Reports, 2021 • August 24, 2021
This study investigates the role of Foxm1, a transcription factor, in spinal cord regeneration in Xenopus tropicalis tadpoles using bulk and single-cell RNA sequencing. The research finds that Foxm1 i...
KEY FINDING: Foxm1 is specifically expressed in the regenerating spinal cord of Xenopus tadpoles, peaking at 3 days post-amputation.