Browse the latest research summaries in the field of covid-19 for spinal cord injury patients and caregivers.
Showing 71-77 of 77 results
STEM CELLS AND DEVELOPMENT, 2020 • May 20, 2020
This letter to the editor critically assesses a published study on the use of bone marrow mesenchymal stem cell-derived exosomes (ExoFlo) for treating severe COVID-19. The authors express concerns reg...
KEY FINDING: The letter identifies a lack of information regarding the characterization, biological properties, and therapeutic actions of the ExoFlo product used in the original study.
Frontiers in Molecular Biosciences, 2020 • December 17, 2020
There are no marketed and effective antiviral drug products or biologics available for the control of SARS-CoV-2, other than symptomatic clinical treatment strategies for COVID-19. The LT receptor anta...
KEY FINDING: Leukotrienes (LTs), particularly cysteinyl-leukotrienes (Cys-LTs) and their receptors, are identified as potential drug targets in modulating various aspects of COVID-19 pathology, including inflammation, thrombosis, vascular damage, and fibrotic response.
International Journal of Infectious Diseases, 2023 • January 10, 2023
This study comprehensively analyzed the prevalence, severity, and characteristics of smell and taste alterations (STAs) in patients infected with the SARS-CoV-2 Omicron variant. The findings suggest t...
KEY FINDING: The prevalence of smell and taste alterations did not significantly decrease during the Omicron dominance compared to earlier phases of the pandemic.
Cell Reports Medicine, 2024 • May 21, 2024
The study analyzes the transcriptome and DNA methylome of fetal germline cells following maternal SARS-CoV-2 infection, finding that infection at early gestational age trivially affects fetal germ cel...
KEY FINDING: Maternal SARS-CoV-2 infection has trivial impacts on fetal germ cell (FGC) development during early gestation, a critical period for germ cell specification and epigenetic reprogramming.
Diagnostics, 2022 • October 22, 2022
The study analyzed 189 convalescent plasma (CP) donations from 66 donors to determine the optimal time span for CP donation based on anti-SARS-CoV-2 anti-S IgG antibody levels. It found a significant ...
KEY FINDING: There is a significant correlation between semi-quantitative SARS-CoV-2 IgG ratio values and in vitro antibody functionality.
BMC Infectious Diseases, 2023 • November 14, 2023
This study aimed to determine the rate of post-COVID-19 syndrome (PCS) among SARS-CoV-2 seropositive blood donors and to investigate the role of Epstein-Barr virus (EBV) reactivation in PCS. The resul...
KEY FINDING: 18% of individuals with asymptomatic or mild SARS-CoV-2 infections experienced PCS symptoms lasting up to one year.
VIEW, 2022 • March 2, 2022
This study reveals that acidosis-related pH promotes SARS-CoV-2 infection by increasing ACE2 expression on the cell membrane, suggesting a positive feedback loop where SARS-CoV-2 infection-induced aci...
KEY FINDING: Acidosis-related pH (6.8) increases the expression of SARS-CoV-2 receptor ACE2 on the cell membrane.