Browse the latest research summaries in the field of dermatology for spinal cord injury patients and caregivers.
Showing 61-70 of 158 results
Int. J. Mol. Sci., 2022 • December 14, 2022
The study validates that burn injury results in sciatic nerve demyelination and that Schwann cell dedifferentiation increases the expression of the immature marker p75 and reduces that of the maturate...
KEY FINDING: Spinal irisin gene delivery attenuates burn injury-induced sciatic nerve demyelination and reduction of neuromuscular junction innervation.
The Journal of Spinal Cord Medicine, 2021 • January 1, 2021
This retrospective study compared the outcomes of 4-week and 6-week post-flap bedrest protocols for patients with SCI undergoing flap surgery for PIs. The study found that the 4-week protocol resulted...
KEY FINDING: Patients in the 4-week protocol group achieved 2-hour sitting an average of 6 days sooner than those in the 6-week protocol group.
Physiological Reports, 2019 • January 1, 2019
This study demonstrates that dendritic spine dysgenesis occurs in ventral horn motor neurons following burn injury, suggesting motor neuron synaptic plasticity. Romidepsin, a Pak1-inhibitor, restored ...
KEY FINDING: Second-degree burn injury significantly affects motor neuron structure within the spinal cord, specifically increasing dendritic spine density.
The Journal of Spinal Cord Medicine, 2015 • January 1, 2015
This retrospective study reviewed the medical records of 1408 patients with SCI, identifying 253 patients who were referred to dermatology for skin lesions. The study aimed to understand dermatologica...
KEY FINDING: The most common dermatological condition was infectious (n = 123, 36.7%) followed by eczematous lesions (n = 109, 32.5%).
The Journal of Spinal Cord Medicine, 2014 • January 1, 2014
The study aimed to determine if individuals with SCI use prescribed wheelchair cushions when traveling in motor vehicles or on commercial airlines. The survey revealed that most participants do not us...
KEY FINDING: Almost all participants used prescribed wheelchair cushions in their wheelchairs.
The Journal of Spinal Cord Medicine, 2015 • July 1, 2015
This pilot study investigated the biochemical profile of pressure ulcer wound fluid in individuals with and without spinal cord injury (SCI). It aimed to determine if differences exist in the concentr...
KEY FINDING: Wound fluid concentrations were significantly different between subjects with SCI and subjects without SCI for total protein concentration and nine analytes, MMP-9, S100A12, S100A8, S100A9, FGF2, IL-1b, TIMP-1, TIMP-2, and TGF-b1.
The Journal of Spinal Cord Medicine, 2014 • January 1, 2014
This systematic review examined 27 studies on electrical stimulation (ES) for pressure ulcer (PU) prevention and treatment in people with spinal cord injuries (SCI). The review found that ES enhanced ...
KEY FINDING: ES enhanced PU healing in all 11 therapeutic studies, suggesting a positive effect of ES on wound closure.
The Journal of Spinal Cord Medicine, 2012 • July 1, 2012
This cross-sectional study assessed modifiable risk factors for severe pressure ulcers (PrUs) in veterans with spinal cord injury (SCI). The study found high rates of co-morbid medical conditions, sub...
KEY FINDING: Veterans with SCI hospitalized for severe PrUs often have multiple co-morbid conditions, averaging 6.7 conditions per patient.
The Journal of Spinal Cord Medicine, 2014 • January 1, 2014
This study used implementation science frameworks to improve the adoption of pressure ulcer prevention best practices in an inpatient spinal cord injury rehabilitation program. The implementation focu...
KEY FINDING: Risk assessment completion rates improved from 29% to 82% following the implementation of best practices.
International Wound Journal, 2017 • March 1, 2017
This study evaluated a structured treatment program for spinal cord-injured patients undergoing pressure ulcer surgery, with a 10-year follow-up. The program showed good initial healing, low ulcer rec...
KEY FINDING: At one month postoperatively, 96% of patients were completely healed.