Browse the latest research summaries in the field of endocrinology for spinal cord injury patients and caregivers.
Showing 121-130 of 211 results
Physiol Rep, 2019 • July 1, 2019
This study investigated the interactive effects of myostatin (Mstn) and AdipoRon on hepatic gene expression and function in a mouse hepatocyte line. Mstn increased fatty acid accumulation and desensit...
KEY FINDING: Myostatin (Mstn) increases fatty acid accumulation and desensitizes cellular responses to insulin in hepatocytes.
Trials, 2019 • January 1, 2019
This study protocol outlines a randomized controlled trial to investigate the acute effects of different upper-body exercise modalities on postprandial metabolic responses in men with spinal cord inju...
KEY FINDING: The study will compare the acute metabolic responses of persons with SCI to two novel, higher-intensity modes of upper-body exercise (CRT and HIIT) with a more traditional form of exercise (MICT) and rest (CON).
Osteoporos Int, 2013 • March 1, 2013
This study assessed circulating proteins as biomarkers of bone status in men with chronic SCI, finding sclerostin significantly associated with bone mineral content and density at all sites tested. Th...
KEY FINDING: Lower sclerostin levels were significantly associated with lower bone mineral content and bone density at all skeletal sites tested.
Annals of Rehabilitation Medicine, 2013 • June 1, 2013
This study investigated the characteristics of abdominal obesity (AO) in community-dwelling individuals with spinal cord injury (SCI) compared to the general population (GP). It assessed factors such ...
KEY FINDING: The prevalence of abdominal obesity was similar in SCI persons (29.2%) and the general population (27.4%).
Neurology, 2013 • November 19, 2013
This study used a large national survey of over 60,000 people to explore the link between spinal cord injury (SCI) and type 2 diabetes. It found that people with SCI had a higher prevalence of type 2 ...
KEY FINDING: SCI was associated with a significant increased odds of type 2 diabetes.
PM R, 2014 • May 1, 2014
Assessment of BMD in children is challenging because of the limitations of DXA in evaluating the growing skeleton. Increasing evidence suggests that bisphosphonates may be beneficial for pediatric dis...
KEY FINDING: Data suggest short-term improvements in BMD, whereas effects on fracture risk remain an area of debate.
Journal of Lifestyle Medicine, 2013 • March 1, 2013
The present review briefly describes the pathophysiological mechanisms underlying SCI, focusing on therapeutic targets and combined melatonin and exercise therapy, which can attenuate secondary injury...
KEY FINDING: Melatonin has been reported to reduce lipid peroxidation levels following injury in animal models of SCI; this may be that because melatonin is a powerful antioxidant itself, and it stimulates other antioxidant enzymes, including catalase, glutathione reductase, peroxidase, and superoxide dismutase
Top Spinal Cord Inj Rehabil, 2007 • January 1, 2007
The prevalence of obesity is increasing, including in individuals with spinal cord injuries (SCI). BMI may not accurately reflect obesity in SCI due to changes in body composition; percent body fat is...
KEY FINDING: Obesity prevalence may be underestimated or unclearly defined following SCI due to the lack of a valid differential tool.
Journal of the Royal Society of Medicine, 1994 • March 1, 1994
This letter to the editor addresses the relationship between rheumatism and thyroid conditions, challenging a prior assertion regarding subacute thyroiditis and autoimmune thyroiditis. The author argu...
KEY FINDING: Subacute thyroiditis is not necessarily an accentuated form of autoimmune thyroiditis; the presence of thyroid antibodies is more likely a consequence of the disease.
Endocrine Connections, 2021 • October 22, 2021
This study investigates the evolutionary conservation and functional divergence of two homologous MC3Rs in the allotetraploid frog Xenopus laevis in vitro. The study clarified the interaction between ...
KEY FINDING: xlMRAP2.L/S enhances α-MSH-stimulated xlMC3Rs signaling and reduces their surface expression.