Endocrinology Research

KEY FINDING: Repeated cold exposure upregulates UCP1 and TMEM26 protein expression in subcutaneous white adipose tissue (WAT) in both lean and obese subjects.

KEY FINDING: Individuals with SCI and normal HDL-C had negligible differences in lipoprotein particle profile compared to able-bodied individuals, except for fewer number and smaller size of HDL-P.

KEY FINDING: There was a significant positive association between lean mass and leptin in men with SCI that was independent of fat.

KEY FINDING: Healthy mice with elevated UnAG levels showed differences in nerve structure compared to normal mice, suggesting a role for UnAG in nerve development. Specifically, UnAG median nerves have a higher density and smaller myelinated fibres than WT nerves.

KEY FINDING: Chronic SCI results in decreased POMC and increased NPY expression in the hypothalamic ARC and PVN.

KEY FINDING: Post-SCI administration of 17b-estradiol improves hindlimb locomotion.

KEY FINDING: The average gonadal response in the SCI and AB groups to each dose of hCG was not significantly different in the hypogonadal or eugonadal subjects.

KEY FINDING: SCI reduced distal femoral and proximal tibial bone mineral density (BMD) by 25 and 16%, respectively, at 56 days.

KEY FINDING: High-level spinal cord injuries are associated with lower glucose tolerance, greater insulin resistance, and impaired lipid profiles compared to lower-level injuries.

KEY FINDING: Zebrafish possess regenerative capabilities in various organs, making them suitable for studying regenerative medicine approaches for endocrine disorders like diabetes mellitus.