Browse the latest research summaries in the field of gastroenterology for spinal cord injury patients and caregivers.
Showing 101-110 of 138 results
Frontiers in Microbiology, 2023 • October 20, 2023
This study demonstrates that DCM induces sexually dimorphic gut dysbiosis in mice, with distinct changes in the gut microbiota composition between male and female mice. The study found that DCM is ass...
KEY FINDING: DCM induces gut dysbiosis in mice, and the dysbiosis is sexually dimorphic, with more pronounced changes in male mice compared to females.
Journal of Nanobiotechnology, 2025 • February 11, 2025
The intestinal microbiome plays an important role in SCI and regulating intestinal microbiome promotes SCI repair. Pectin-Zein-IPA NPs treatment improves motor function recovery, inhibits the activati...
KEY FINDING: Pec-Zein-IPA NPs treatment improves motor function recovery and activates AKT/Nrf-2 signaling pathway following SCI.
Neural Regeneration Research, 2016 • June 1, 2016
This study investigates the central neuromechanisms underlying the control of intragastric pressure through acupuncture at Zusanli (ST36) in rats, with a focus on the upper cervical cord's role. The f...
KEY FINDING: Zusanli acupuncture effectively elevated intragastric pressure, even after complete dorsal cord transection.
The Journal of Spinal Cord Medicine, 2020 • January 1, 2020
This study introduces a novel nerve transfer technique to restore anorectal function in rats after spinal cord injury (SCI). The procedure involves creating an artificial reflex arc by anastomosing L5...
KEY FINDING: The study found that the new nerve pathway connecting the spine to the anorectal muscles was successfully established in rats with SCI.
Neural Regeneration Research, 2013 • August 1, 2013
This study explored the mechanism of electroacupuncture at He-Mu points in treating visceral hypersensitivity in irritable bowel syndrome. The study demonstrated that electroacupuncture reduced P2X4 r...
KEY FINDING: Electroacupuncture at Shangjuxu (ST37) and Tianshu (ST25) significantly reduced abdominal withdrawal reflex scores in rats with visceral hypersensitivity.
Neural Regen Res, 2012 • October 1, 2012
The study investigates the protective effects of pre-moxibustion at Zusanli (ST36) on gastric mucosal lesions in rats induced by absolute alcohol. It examines the role of heat shock protein 70 (HSP70)...
KEY FINDING: Pre-moxibustion at Zusanli (ST36) can protect the gastric mucosa against lesioning in rats.
Neural Regen Res, 2012 • May 1, 2012
This study aimed to verify if rat spinal cord prokineticin 1 and its receptor contribute to the analgesic effect of suspended moxibustion in a rat model of irritable bowel syndrome where rats display ...
KEY FINDING: Suspended moxibustion at Tianshu (ST25) significantly decreased visceral sensitivity to colorectal distention in rats with CVH.
Brain Sci., 2025 • February 14, 2025
Spinal cord injury (SCI) leads to secondary complications like gut dysbiosis (GD) and NLRP3 inflammasome activation, impacting mental health due to disrupted gut microbiome and inflammatory processes....
KEY FINDING: Gut dysbiosis (GD) and activation of the NLRP3 inflammasome are significant secondary complications after spinal cord injury (SCI), impacting mental health.
World Journal of Gastroenterology, 2025 • February 28, 2025
Neurosurgical patients face a high risk of stress ulcers and gastrointestinal bleeding due to factors like brain injury, spinal cord injury, and increased intracranial pressure. The review discusses b...
KEY FINDING: Stress ulcers are a significant risk for neurosurgical patients, particularly those with severe brain injuries and elevated intracranial pressure.
Top Spinal Cord Inj Rehabil, 2019 • August 7, 2018
This systematic review aimed to identify and classify outcome measures assessing the influence of neurogenic bowel dysfunction (NBD) on quality of life (QoL) and related constructs after spinal cord i...
KEY FINDING: Thirteen QoL outcome tools were identified, five objective and eight subjective, used in studies assessing the influence of NBD on QoL in SCI.