Browse the latest research summaries in the field of immunology for spinal cord injury patients and caregivers.
Showing 31-40 of 620 results
World Journal of Clinical Cases, 2023 • December 26, 2023
This case report describes a 70-year-old female who developed a spinal cord infarction attributed to acute SARS-CoV-2 infection, resulting in paraplegia and subsequent post-acute sequelae of COVID-19 ...
KEY FINDING: Spinal cord infarction can occur as a rare complication following acute SARS-CoV-2 infection, leading to significant neurological disability.
Neurosciences, 2024 • January 1, 2024
This study analyzed urine culture results from 151 SCI patients with UTIs to determine common causative organisms and their antibiotic sensitivities based on different voiding methods. The most common...
KEY FINDING: E. coli was found to be the most common cause of UTIs overall, especially in patients using self-intermittent catheterization (SIC) and indwelling catheters (IDC).
Spinal Cord Series and Cases, 2024 • January 22, 2024
This retrospective cross-sectional study identified that individuals with SCI received outpatient antibiotic prescriptions from multiple sources, with rostered primary care practice physicians being t...
KEY FINDING: Rostered-primary care practice physicians prescribed the majority (58.9%) of dispensed antibiotics to the SCI cohort.
Scientific Reports, 2024 • February 10, 2024
This retrospective study analyzed data from 538 hospitalized patients with SCI in China between 2014 and 2023 to determine the incidence and risk factors for urinary tract infections (UTIs). The study...
KEY FINDING: The incidence of UTI in hospitalized patients with SCI in China was found to be 49.8%.
Frontiers in Immunology, 2024 • January 29, 2024
This review comprehensively describes the mechanisms underlying the inflammatory response and Treg cell regulation subsequent to spinal cord injury, with a specific focus on exploring the potential mech...
KEY FINDING: Inflammation following spinal cord injury involves the release of mediators like cytokines and chemokines, which stimulate sensory neurons and increase neuronal excitability, leading to pain perception.
Infection Prevention in Practice, 2024 • January 27, 2024
This case series investigates the use of faecal microbiota transplantation (FMT) for decolonizing multidrug-resistant (MDR) bacteria in seven spinal cord injury (SCI) patients. The study found that FM...
KEY FINDING: FMT was successful in decolonizing MDR bacteria in five out of seven spinal cord injury patients.
Curr. Issues Mol. Biol., 2024 • February 1, 2024
This study investigates the effects of nicotinamide riboside (NR) supplementation on spinal cord injury (SCI) in mice. The findings indicate that NR can effectively increase NAD+ levels in spinal cord...
KEY FINDING: NR supplementation significantly elevated NAD+ levels in the spinal cord tissue of mice after SCI, reversing the decrease typically observed after such injuries.
Diagnostics, 2024 • February 11, 2024
This case report describes a 65-year-old patient with chronic high cervical tetraplegia who developed an esophageal rupture with a concomitant cervical abscess following previous cervical surgery. The...
KEY FINDING: Esophageal rupture can occur as a rare complication following cervical surgery, even in chronic cases.
J. Clin. Med., 2024 • February 19, 2024
This case report describes a 52-year-old female who developed NMOSD-induced complete spinal cord injury after receiving the Pfizer–BioNTech COVID-19 vaccine. The patient presented with pain in both ey...
KEY FINDING: The patient experienced a remarkable neurological recovery, transitioning from complete spinal cord injury (AIS-A) to functional independence (AIS-E) after intensive treatment and rehabilitation.
Frontiers in Immunology, 2024 • March 13, 2024
Spinal cord injury results in tissue debris and an inflammatory microenvironment that inhibits nerve regeneration; macrophages, the primary cells for debris removal, can become foam cells, worsening i...
KEY FINDING: Foam cells persist in the lesion site after SCI and mediate chronic inflammation, which hampers nerve repair.