Browse the latest research summaries in the field of musculoskeletal medicine for spinal cord injury patients and caregivers.
Showing 101-110 of 269 results
Spinal Cord, 2019 • July 15, 2019
This study investigated the association between bone turnover markers and fall-related fractures in 106 individuals with spinal cord injury (SCI) over a 1-year follow-up period. The primary finding wa...
KEY FINDING: High serum levels of carboxy terminal collagen crosslinks (CTX) increased the odds of being in the fracture group.
The Journal of Spinal Cord Medicine, 2020 • January 1, 2020
The study reviews historical literature on non-surgical management of thoracolumbar fracture dislocations, mainly involving bed rest and postural reduction, to compare with modern surgical outcomes. R...
KEY FINDING: Non-surgical management often resulted in residual spinal deformity and a high rate of post-treatment pain syndromes.
Physiological Reports, 2020 • January 1, 2020
The study investigated whether muscle disuse following spinal cord injury (SCI) induces cellular senescence and markers of senescence-associated secretory phenotypes (SASPs) in paralyzed skeletal musc...
KEY FINDING: SCI soleus muscle displayed 2- to 3-fold higher total p53 protein expression at 2 weeks, and at 1 and 2 months when compared with Sham.
Asian Spine Journal, 2020 • December 1, 2020
This prospective study evaluated trunk musculature and intervertebral discs in SCI patients with thoracolumbar fractures using MRI. The study revealed significant decreases in disc and trunk parameter...
KEY FINDING: Significant decreases were observed in disc parameters (disc angle, skin angle, CSA, disc height) and trunk parameters (trunk width, trunk depth, CSA of lumbar muscles) during the first 3 months after SCI.
The Journal of Spinal Cord Medicine, 2020 • May 1, 2020
This study examined the impact of a functional electrical stimulation (FES) rowing program on bone mineral density (BMD) in individuals within two years of a spinal cord injury (SCI). The results sugg...
KEY FINDING: Trabecular BMD in the femur and tibia decreased for all participants in T0-1, but the rate of loss slowed or reversed between T1-2, with little-to-no bone loss for most participants during T2-3.
JBMR Plus, 2020 • August 1, 2020
This study evaluated the effectiveness of denosumab in preserving bone mineral density (BMD) in individuals with subacute spinal cord injury (SCI). The findings indicate that denosumab maintained BMD ...
KEY FINDING: Denosumab maintained aBMD at the distal femur and proximal tibia in persons with a subacute motor-complete SCI.
JOURNAL OF REHABILITATION MEDICINE, 2019 • October 4, 2019
Sacral insufficiency fractures should be considered in differential diagnosis as a cause of autonomic dysreflexia and other vague symptoms in patients with spinal cord injury. Radiological investigati...
KEY FINDING: Radiological investigation with computed tomography of the abdomen and pelvis demonstrated sacral insufficiency fractures in both cases.
The Journal of Spinal Cord Medicine, 2020 • October 1, 2020
This study aimed to identify T-score values at the total hip (TH) and femoral neck (FN) that correspond to the cutoff value of <0.60 g/cm2 for heightened risk of fracture at the distal femur (DF) and ...
KEY FINDING: aBMD at the DF and PT regions were significant predictors of T-score at the TH (R2 = 0.63, P < 0.001 and R2 = 0.65, P < 0.001) and FN (R2 = 0.55, P < 0.001 and R2 = 0.58, P < 0.001).
The Journal of Spinal Cord Medicine, 2014 • January 1, 2014
This study assessed bone mineral density (BMD) in Iranian patients with chronic spinal cord injury (SCI), examining the impact of demographic, injury-related, and dietary factors. The research involve...
KEY FINDING: Older male patients exhibited lower BMD specifically in spinal vertebrae.
The Journal of Spinal Cord Medicine, 2015 • January 1, 2015
This retrospective study investigated the protective effect of oral alendronate (ALN) intake on the appearance of heterotopic ossification (HO) in patients with spinal cord injury (SCI). The study fou...
KEY FINDING: There was no statistically significant difference in the incidence of HO in patients receiving oral ALN compared to those not receiving it.